ABCB7-PA FISH Probe
The ABCB7-PA FISH probe is designed to hybridize to the ABCB7-PA gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ABCB7-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| ABCB7-20-RE | 20 (40 μL) | 200 μL |  |
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| ABCB7-20-GO | 20 (40 μL) | 200 μL |  |
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| ABCB7-20-GR | 20 (40 μL) | 200 μL |  |
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| ABCB7-20-AQ | 20 (40 μL) | 200 μL |  |
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| ABCB7-20-DIG | 20 (40 μL) | 200 μL |  |
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| ABCB7-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This gene encodes a half-transporter involved in the transport of heme from the mitochondria to the cytosol. With iron/sulfur cluster precursors as its substrates, this protein may play a role in metal homeostasis. Mutations in this gene have been associated with mitochondrial iron accumulation and isodicentric (X)(q13) and sideroblastic anemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2012]
Gene Details
Gene Symbol: ABCB7
Gene Name: ATP Binding Cassette Subfamily B Member 7
Chromosome: CHRX: 74273104-74376132
Locus: Xq13.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: ABCB7-PA FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: ABCB7-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping