AA-NAT FISH Probe
The AA-NAT FISH probe is designed to hybridize to the AA-NAT gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| AANAT-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| AANAT-20-RE | 20 (40 μL) | 200 μL |  |
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| AANAT-20-GO | 20 (40 μL) | 200 μL |  |
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| AANAT-20-GR | 20 (40 μL) | 200 μL |  |
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| AANAT-20-AQ | 20 (40 μL) | 200 μL |  |
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| AANAT-20-DIG | 20 (40 μL) | 200 μL |  |
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| AANAT-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene belongs to the acetyltransferase superfamily. It is the penultimate enzyme in melatonin synthesis and controls the night/day rhythm in melatonin production in the vertebrate pineal gland. Melatonin is essential for the function of the circadian clock that influences activity and sleep. This enzyme is regulated by cAMP-dependent phosphorylation that promotes its interaction with 14-3-3 proteins and thus protects the enzyme against proteasomal degradation. This gene may contribute to numerous genetic diseases such as delayed sleep phase syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]
Gene Details
Gene Symbol: AANAT
Gene Name: Aralkylamine N-acetyltransferase
Chromosome: CHR17: 74449432-74466199
Locus: 17q25.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: AA-NAT FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: AANAT-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping