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A2ML1 FISH Probe

The A2ML1 FISH probe is designed to hybridize to the A2ML1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

SKU Test Kits Buffer Dye Color Order Now
A2ML1-20-OR  (Standard Design) 20 (40 μL) 200 μL
A2ML1-20-RE 20 (40 μL) 200 μL
A2ML1-20-GO 20 (40 μL) 200 μL
A2ML1-20-GR 20 (40 μL) 200 μL
A2ML1-20-AQ 20 (40 μL) 200 μL
A2ML1-20-DIG 20 (40 μL) 200 μL
A2ML1-20-BIO 20 (40 μL) 200 μL

Gene Summary

This gene encodes a member of the alpha-macroglobulin superfamily. The encoded protein is thought to be an N-glycosylated monomeric protein that acts as an inhibitor of several proteases. It has been shown to form covalent interactions with proteases, and has been reported as the p170 antigen recognized by autoantibodies in the autoimmune disease paraneoplastic pemphigus (PNP; PMID:20805888). Mutations in these gene have also been associated with some cases of Noonan syndrome (NS; PMID:24939586) as well as some cases of otitis media (PMID:26121085). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2015]

Gene Details

Gene Symbol: A2ML1

Gene Name: Alpha-2-macroglobulin Like 1

Chromosome: CHR12: 8975149-9029377

Locus: 12p13.31

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Scientific Citations

There are currently no FISH related citations for this gene.

Product Details

Product: A2ML1 FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: A2ML1-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping