A2ML1 FISH Probe
The A2ML1 FISH probe is designed to hybridize to the A2ML1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| A2ML1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| A2ML1-20-RE | 20 (40 μL) | 200 μL |  |
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| A2ML1-20-GO | 20 (40 μL) | 200 μL |  |
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| A2ML1-20-GR | 20 (40 μL) | 200 μL |  |
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| A2ML1-20-AQ | 20 (40 μL) | 200 μL |  |
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| A2ML1-20-DIG | 20 (40 μL) | 200 μL |  |
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| A2ML1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a member of the alpha-macroglobulin superfamily. The encoded protein is thought to be an N-glycosylated monomeric protein that acts as an inhibitor of several proteases. It has been shown to form covalent interactions with proteases, and has been reported as the p170 antigen recognized by autoantibodies in the autoimmune disease paraneoplastic pemphigus (PNP; PMID:20805888). Mutations in these gene have also been associated with some cases of Noonan syndrome (NS; PMID:24939586) as well as some cases of otitis media (PMID:26121085). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2015]
Gene Details
Gene Symbol: A2ML1
Gene Name: Alpha-2-macroglobulin Like 1
Chromosome: CHR12: 8975149-9029377
Locus: 12p13.31
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: A2ML1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: A2ML1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping