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A1CF FISH Probe

The A1CF FISH probe is designed to hybridize to the A1CF gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

SKU Test Kits Buffer Dye Color Order Now
A1CF-20-OR  (Standard Design) 20 (40 μL) 200 μL
A1CF-20-RE 20 (40 μL) 200 μL
A1CF-20-GO 20 (40 μL) 200 μL
A1CF-20-GR 20 (40 μL) 200 μL
A1CF-20-AQ 20 (40 μL) 200 μL
A1CF-20-DIG 20 (40 μL) 200 μL
A1CF-20-BIO 20 (40 μL) 200 μL

Gene Summary

Mammalian apolipoprotein B mRNA undergoes site-specific C to U deamination, which is mediated by a multi-component enzyme complex containing a minimal core composed of APOBEC-1 and a complementation factor encoded by this gene. The gene product has three non-identical RNA recognition motifs and belongs to the hnRNP R family of RNA-binding proteins. It has been proposed that this complementation factor functions as an RNA-binding subunit and docks APOBEC-1 to deaminate the upstream cytidine. Studies suggest that the protein may also be involved in other RNA editing or RNA processing events. Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Nov 2010]

Gene Details

Gene Symbol: A1CF

Gene Name: APOBEC1 Complementation Factor

Chromosome: CHR10: 52559168-52645435

Locus: 10q11.23

Gene Diseases

The A1CF gene has been associated with the following diseases:

Disease Name
2-Hydroxyglutaricaciduria
Brachymesophalangy 2 And 5
Campomelia Cumming Type
Dermatoosteolysis Kirghizian Type
Human Balantidiasis
Oroticaciduria 1
Passovoy Factor
PHACE Association
Primary Dysautonomias
Sakoda Complex
Syringomas, Multiple
Translocation, Genetic

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Scientific Citations

There are currently no FISH related citations for this gene.

Product Details

Product: A1CF FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: A1CF-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping