A-SCS FISH Probe
The A-SCS FISH probe is designed to hybridize to the A-SCS gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
SUCLA2-20-OR (Standard Design) | 20 (40 μL) | 200 μL | ||
SUCLA2-20-RE | 20 (40 μL) | 200 μL | ||
SUCLA2-20-GO | 20 (40 μL) | 200 μL | ||
SUCLA2-20-GR | 20 (40 μL) | 200 μL | ||
SUCLA2-20-AQ | 20 (40 μL) | 200 μL | ||
SUCLA2-20-DIG | 20 (40 μL) | 200 μL | ||
SUCLA2-20-BIO | 20 (40 μL) | 200 μL |
Gene Summary
Succinyl-CoA synthetase (SCS) is a mitochondrial matrix enzyme that acts as a heterodimer, being composed of an invariant alpha subunit and a substrate-specific beta subunit. The protein encoded by this gene is an ATP-specific SCS beta subunit that dimerizes with the SCS alpha subunit to form SCS-A, an essential component of the tricarboxylic acid cycle. SCS-A hydrolyzes ATP to convert succinate to succinyl-CoA. Defects in this gene are a cause of myopathic mitochondrial DNA depletion syndrome. A pseudogene of this gene has been found on chromosome 6. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: SUCLA2
Gene Name: Succinate-CoA Ligase ADP-forming Beta Subunit
Chromosome: CHR13: 48516790-48575462
Locus: 13q14.2
FISH Probe Protocols
Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: A-SCS FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: SUCLA2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping