61B3-R FISH Probe
The 61B3-R FISH probe is designed to hybridize to the 61B3-R gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| MID1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| MID1-20-RE | 20 (40 μL) | 200 μL |  |
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| MID1-20-GO | 20 (40 μL) | 200 μL |  |
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| MID1-20-GR | 20 (40 μL) | 200 μL |  |
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| MID1-20-AQ | 20 (40 μL) | 200 μL |  |
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| MID1-20-DIG | 20 (40 μL) | 200 μL |  |
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| MID1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is a member of the tripartite motif (TRIM) family, also known as the 'RING-B box-coiled coil' (RBCC) subgroup of RING finger proteins. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein forms homodimers which associate with microtubules in the cytoplasm. The protein is likely involved in the formation of multiprotein structures acting as anchor points to microtubules. Mutations in this gene have been associated with the X-linked form of Opitz syndrome, which is characterized by midline abnormalities such as cleft lip, laryngeal cleft, heart defects, hypospadias, and agenesis of the corpus callosum. This gene was also the first example of a gene subject to X inactivation in human while escaping it in mouse. Alternative promoter use, alternative splicing and alternative polyadenylation result in multiple transcript variants that have different tissue specificities. [provided by RefSeq, Dec 2016]
Gene Details
Gene Symbol: MID1
Gene Name: Midline 1
Chromosome: CHRX: 10413349-10851809
Locus: Xp22.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: 61B3-R FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: MID1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping