60SRPL5 FISH Probe
The 60SRPL5 FISH probe is designed to hybridize to the 60SRPL5 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| RPL5-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| RPL5-20-RE | 20 (40 μL) | 200 μL |  |
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| RPL5-20-GO | 20 (40 μL) | 200 μL |  |
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| RPL5-20-GR | 20 (40 μL) | 200 μL |  |
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| RPL5-20-AQ | 20 (40 μL) | 200 μL |  |
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| RPL5-20-DIG | 20 (40 μL) | 200 μL |  |
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| RPL5-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of four RNA species and approximately 80 structurally distinct proteins. This gene encodes a member of the L18P family of ribosomal proteins and component of the 60S subunit. The encoded protein binds 5S rRNA to form a stable complex called the 5S ribonucleoprotein particle (RNP), which is necessary for the transport of nonribosome-associated cytoplasmic 5S rRNA to the nucleolus for assembly into ribosomes. The encoded protein may also function to inhibit tumorigenesis through the activation of downstream tumor suppressors and the downregulation of oncoprotein expression. Mutations in this gene have been identified in patients with Diamond-Blackfan Anemia (DBA). This gene is co-transcribed with the small nucleolar RNA gene U21, which is located in its fifth intron. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed throughout the genome. [provided by RefSeq, Mar 2017]
Gene Details
Gene Symbol: RPL5
Gene Name: Ribosomal Protein L5
Chromosome: CHR1: 93297593-93307481
Locus: 1p22.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: 60SRPL5 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: RPL5-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping