60S RIBOSOMAL PROTEIN L22 FISH Probe
The 60S RIBOSOMAL PROTEIN L22 FISH probe is designed to hybridize to the 60S RIBOSOMAL PROTEIN L22 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| RPL22-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| RPL22-20-RE | 20 (40 μL) | 200 μL |  |
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| RPL22-20-GO | 20 (40 μL) | 200 μL |  |
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| RPL22-20-GR | 20 (40 μL) | 200 μL |  |
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| RPL22-20-AQ | 20 (40 μL) | 200 μL |  |
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| RPL22-20-DIG | 20 (40 μL) | 200 μL |  |
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| RPL22-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a cytoplasmic ribosomal protein that is a component of the 60S subunit. The protein belongs to the L22E family of ribosomal proteins. Its initiating methionine residue is post-translationally removed. The protein can bind specifically to Epstein-Barr virus-encoded RNAs (EBERs) 1 and 2. The mouse protein has been shown to be capable of binding to heparin. Transcript variants utilizing alternative polyA signals exist. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. It was previously thought that this gene mapped to 3q26 and that it was fused to the acute myeloid leukemia 1 (AML1) gene located at 21q22 in some therapy-related myelodysplastic syndrome patients with 3;21 translocations; however, these fusions actually involve a ribosomal protein L22 pseudogene located at 3q26, and this gene actually maps to 1p36.3-p36.2. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: RPL22
Gene Name: Ribosomal Protein L22
Chromosome: CHR1: 6245079-6259679
Locus: 1p36.31
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: 60S RIBOSOMAL PROTEIN L22 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: RPL22-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping