5-HT FISH Probe
The 5-HT FISH probe is designed to hybridize to the 5-HT gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| DDC-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
|
| DDC-20-RE | 20 (40 μL) | 200 μL |  |
|
| DDC-20-GO | 20 (40 μL) | 200 μL |  |
|
| DDC-20-GR | 20 (40 μL) | 200 μL |  |
|
| DDC-20-AQ | 20 (40 μL) | 200 μL |  |
|
| DDC-20-DIG | 20 (40 μL) | 200 μL |  |
|
| DDC-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The encoded protein catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine. Defects in this gene are the cause of aromatic L-amino-acid decarboxylase deficiency (AADCD). AADCD deficiency is an inborn error in neurotransmitter metabolism that leads to combined serotonin and catecholamine deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jun 2011]
Gene Details
Gene Symbol: DDC
Gene Name: Dopa Decarboxylase
Chromosome: CHR7: 50526133-50633154
Locus: 7p12.2-p12.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|
Customer Publications
Product Details
Product: 5-HT FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: DDC-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping