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5-HT FISH Probe

The 5-HT FISH probe is designed to hybridize to the 5-HT gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
DDC-20-OR  (Standard Design) 20 (40 μL) 200 μL
DDC-20-RE 20 (40 μL) 200 μL
DDC-20-GO 20 (40 μL) 200 μL
DDC-20-GR 20 (40 μL) 200 μL
DDC-20-AQ 20 (40 μL) 200 μL
DDC-20-DIG 20 (40 μL) 200 μL
DDC-20-BIO 20 (40 μL) 200 μL

Gene Summary

The encoded protein catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine. Defects in this gene are the cause of aromatic L-amino-acid decarboxylase deficiency (AADCD). AADCD deficiency is an inborn error in neurotransmitter metabolism that leads to combined serotonin and catecholamine deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jun 2011]

Gene Details

Gene Symbol: DDC

Gene Name: Dopa Decarboxylase

Chromosome: CHR7: 50526133-50633154

Locus: 7p12.2-p12.1

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: 5-HT FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: DDC-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping