4-1BBL FISH Probe
The 4-1BBL FISH probe is designed to hybridize to the 4-1BBL gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| TNFSF9-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| TNFSF9-20-RE | 20 (40 μL) | 200 μL |  |
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| TNFSF9-20-GO | 20 (40 μL) | 200 μL |  |
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| TNFSF9-20-GR | 20 (40 μL) | 200 μL |  |
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| TNFSF9-20-AQ | 20 (40 μL) | 200 μL |  |
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| TNFSF9-20-DIG | 20 (40 μL) | 200 μL |  |
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| TNFSF9-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This transmembrane cytokine is a bidirectional signal transducer that acts as a ligand for TNFRSF9/4-1BB, which is a costimulatory receptor molecule in T lymphocytes. This cytokine and its receptor are involved in the antigen presentation process and in the generation of cytotoxic T cells. The receptor TNFRSF9/4-1BB is absent from resting T lymphocytes but rapidly expressed upon antigenic stimulation. The ligand encoded by this gene, TNFSF9/4-1BBL, has been shown to reactivate anergic T lymphocytes in addition to promoting T lymphocyte proliferation. This cytokine has also been shown to be required for the optimal CD8 responses in CD8 T cells. This cytokine is expressed in carcinoma cell lines, and is thought to be involved in T cell-tumor cell interaction.[provided by RefSeq, Oct 2008]
Gene Details
Gene Symbol: TNFSF9
Gene Name: TNF Superfamily Member 9
Chromosome: CHR19: 6531009-6535939
Locus: 19p13.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: 4-1BBL FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: TNFSF9-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping