3MC1 FISH Probe
The 3MC1 FISH probe is designed to hybridize to the 3MC1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| MASP1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| MASP1-20-RE | 20 (40 μL) | 200 μL |  |
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| MASP1-20-GO | 20 (40 μL) | 200 μL |  |
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| MASP1-20-GR | 20 (40 μL) | 200 μL |  |
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| MASP1-20-AQ | 20 (40 μL) | 200 μL |  |
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| MASP1-20-DIG | 20 (40 μL) | 200 μL |  |
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| MASP1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a serine protease that functions as a component of the lectin pathway of complement activation. The complement pathway plays an essential role in the innate and adaptive immune response. The encoded protein is synthesized as a zymogen and is activated when it complexes with the pathogen recognition molecules of lectin pathway, the mannose-binding lectin and the ficolins. This protein is not directly involved in complement activation but may play a role as an amplifier of complement activation by cleaving complement C2 or by activating another complement serine protease, MASP-2. The encoded protein is also able to cleave fibrinogen and factor XIII and may may be involved in coagulation. A splice variant of this gene which lacks the serine protease domain functions as an inhibitor of the complement pathway. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Apr 2010]
Gene Details
Gene Symbol: MASP1
Gene Name: Mannan Binding Lectin Serine Peptidase 1
Chromosome: CHR3: 186933872-187009810
Locus: 3q27.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: 3MC1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: MASP1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping