2BP1 FISH Probe
The 2BP1 FISH probe is designed to hybridize to the 2BP1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| RBFOX1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| RBFOX1-20-RE | 20 (40 μL) | 200 μL |  |
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| RBFOX1-20-GO | 20 (40 μL) | 200 μL |  |
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| RBFOX1-20-GR | 20 (40 μL) | 200 μL |  |
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| RBFOX1-20-AQ | 20 (40 μL) | 200 μL |  |
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| RBFOX1-20-DIG | 20 (40 μL) | 200 μL |  |
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| RBFOX1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The Fox-1 family of RNA-binding proteins is evolutionarily conserved, and regulates tissue-specific alternative splicing in metazoa. Fox-1 recognizes a (U)GCAUG stretch in regulated exons or in flanking introns. The protein binds to the C-terminus of ataxin-2 and may contribute to the restricted pathology of spinocerebellar ataxia type 2 (SCA2). Ataxin-2 is the product of the SCA2 gene which causes familial neurodegenerative diseases. Fox-1 and ataxin-2 are both localized in the trans-Golgi network. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]
Gene Details
Gene Symbol: RBFOX1
Gene Name: RNA Binding Fox-1 Homolog 1
Chromosome: CHR16: 6069131-7763340
Locus: 16p13.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: 2BP1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: RBFOX1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping