123F2 FISH Probe
The 123F2 FISH probe is designed to hybridize to the 123F2 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| RASSF1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| RASSF1-20-RE | 20 (40 μL) | 200 μL |  |
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| RASSF1-20-GO | 20 (40 μL) | 200 μL |  |
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| RASSF1-20-GR | 20 (40 μL) | 200 μL |  |
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| RASSF1-20-AQ | 20 (40 μL) | 200 μL |  |
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| RASSF1-20-DIG | 20 (40 μL) | 200 μL |  |
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| RASSF1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a protein similar to the RAS effector proteins. Loss or altered expression of this gene has been associated with the pathogenesis of a variety of cancers, which suggests the tumor suppressor function of this gene. The inactivation of this gene was found to be correlated with the hypermethylation of its CpG-island promoter region. The encoded protein was found to interact with DNA repair protein XPA. The protein was also shown to inhibit the accumulation of cyclin D1, and thus induce cell cycle arrest. Several alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, May 2011]
Gene Details
Gene Symbol: RASSF1
Gene Name: Ras Association Domain Family Member 1
Chromosome: CHR3: 50367216-50378367
Locus: 3p21.31
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: 123F2 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: RASSF1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping