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ZNF709-CD177 Fusion FISH Probe

The ZNF709-CD177 Fusion FISH Probe is used to confirm a fusion of the ZNF709 and CD177 genes. The fusion of the ZNF709 and CD177 genes has been associated with Ovarian Serous Cystadenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
ZNF709-CD177-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
ZNF709-CD177-20-RERE 20 (40 μL) 200 μL
ZNF709-CD177-20-REOR 20 (40 μL) 200 μL
ZNF709-CD177-20-REGO 20 (40 μL) 200 μL
ZNF709-CD177-20-REGR 20 (40 μL) 200 μL
ZNF709-CD177-20-REAQ 20 (40 μL) 200 μL
ZNF709-CD177-20-ORRE 20 (40 μL) 200 μL
ZNF709-CD177-20-OROR 20 (40 μL) 200 μL
ZNF709-CD177-20-ORGO 20 (40 μL) 200 μL
ZNF709-CD177-20-ORAQ 20 (40 μL) 200 μL
ZNF709-CD177-20-GORE 20 (40 μL) 200 μL
ZNF709-CD177-20-GOOR 20 (40 μL) 200 μL
ZNF709-CD177-20-GOGO 20 (40 μL) 200 μL
ZNF709-CD177-20-GOGR 20 (40 μL) 200 μL
ZNF709-CD177-20-GOAQ 20 (40 μL) 200 μL
ZNF709-CD177-20-GRRE 20 (40 μL) 200 μL
ZNF709-CD177-20-GROR 20 (40 μL) 200 μL
ZNF709-CD177-20-GRGO 20 (40 μL) 200 μL
ZNF709-CD177-20-GRGR 20 (40 μL) 200 μL
ZNF709-CD177-20-GRAQ 20 (40 μL) 200 μL
ZNF709-CD177-20-AQRE 20 (40 μL) 200 μL
ZNF709-CD177-20-AQOR 20 (40 μL) 200 μL
ZNF709-CD177-20-AQGO 20 (40 μL) 200 μL
ZNF709-CD177-20-AQGR 20 (40 μL) 200 μL
ZNF709-CD177-20-AQAQ 20 (40 μL) 200 μL

CD177 Gene Summary

This gene encodes a glycosyl-phosphatidylinositol (GPI)-linked cell surface glycoprotein that plays a role in neutrophil activation. The protein can bind platelet endothelial cell adhesion molecule-1 and function in neutrophil transmigration. Mutations in this gene are associated with myeloproliferative diseases. Over-expression of this gene has been found in patients with polycythemia rubra vera. Autoantibodies against the protein may result in pulmonary transfusion reactions, and it may be involved in Wegener's granulomatosis. A related pseudogene, which is adjacent to this gene on chromosome 19, has been identified. [provided by RefSeq, Apr 2014]

Gene Name: CD177 Molecule

Chromosome: CHR19: 43857824 -43867480

Locus: 19q13.31

ZNF709 Gene Summary

The Zinc Finger Protein 709 (ZNF709) gene is located on chr19 :12571997-12595632 at 19p13.2.

Gene Name: Zinc Finger Protein 709

Chromosome: CHR19: 12571997 -12595632

Locus: 19p13.2

Gene Diseases

The ZNF709 CD177 Fusion has been associated with the following diseases:

Disease Name
Ovarian Serous Cystadenocarcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.