ZNF699-NR1I2 Fusion FISH Probe
The ZNF699-NR1I2 Fusion FISH Probe is used to confirm a fusion of the ZNF699 and NR1I2 genes. The fusion of the ZNF699 and NR1I2 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ZNF699-NR1I2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ZNF699-NR1I2-20-RERE | 20 (40 μL) | 200 μL |
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| ZNF699-NR1I2-20-REOR | 20 (40 μL) | 200 μL |
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| ZNF699-NR1I2-20-REGO | 20 (40 μL) | 200 μL |
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| ZNF699-NR1I2-20-REGR | 20 (40 μL) | 200 μL |
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| ZNF699-NR1I2-20-REAQ | 20 (40 μL) | 200 μL |
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| ZNF699-NR1I2-20-ORRE | 20 (40 μL) | 200 μL |
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| ZNF699-NR1I2-20-OROR | 20 (40 μL) | 200 μL |
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| ZNF699-NR1I2-20-ORGO | 20 (40 μL) | 200 μL |
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| ZNF699-NR1I2-20-ORAQ | 20 (40 μL) | 200 μL |
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| ZNF699-NR1I2-20-GORE | 20 (40 μL) | 200 μL |
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| ZNF699-NR1I2-20-GOOR | 20 (40 μL) | 200 μL |
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| ZNF699-NR1I2-20-GOGO | 20 (40 μL) | 200 μL |
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| ZNF699-NR1I2-20-GOGR | 20 (40 μL) | 200 μL |
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| ZNF699-NR1I2-20-GOAQ | 20 (40 μL) | 200 μL |
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| ZNF699-NR1I2-20-GRRE | 20 (40 μL) | 200 μL |
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| ZNF699-NR1I2-20-GROR | 20 (40 μL) | 200 μL |
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| ZNF699-NR1I2-20-GRGO | 20 (40 μL) | 200 μL |
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| ZNF699-NR1I2-20-GRGR | 20 (40 μL) | 200 μL |
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| ZNF699-NR1I2-20-GRAQ | 20 (40 μL) | 200 μL |
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| ZNF699-NR1I2-20-AQRE | 20 (40 μL) | 200 μL |
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| ZNF699-NR1I2-20-AQOR | 20 (40 μL) | 200 μL |
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| ZNF699-NR1I2-20-AQGO | 20 (40 μL) | 200 μL |
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| ZNF699-NR1I2-20-AQGR | 20 (40 μL) | 200 μL |
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| ZNF699-NR1I2-20-AQAQ | 20 (40 μL) | 200 μL |
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NR1I2 Gene Summary
This gene product belongs to the nuclear receptor superfamily, members of which are transcription factors characterized by a ligand-binding domain and a DNA-binding domain. The encoded protein is a transcriptional regulator of the cytochrome P450 gene CYP3A4, binding to the response element of the CYP3A4 promoter as a heterodimer with the 9-cis retinoic acid receptor RXR. It is activated by a range of compounds that induce CYP3A4, including dexamethasone and rifampicin. Several alternatively spliced transcripts encoding different isoforms, some of which use non-AUG (CUG) translation initiation codon, have been described for this gene. Additional transcript variants exist, however, they have not been fully characterized. [provided by RefSeq, Jul 2008]
Gene Name: Nuclear Receptor Subfamily 1 Group I Member 2
Chromosome: CHR3: 119499330 -119537332
Locus: 3q13.33
ZNF699 Gene Summary
The Zinc Finger Protein 699 (ZNF699) gene is located on chr19 :9405985-9415795 at 19p13.2.
Gene Name: Zinc Finger Protein 699
Chromosome: CHR19: 9405985 -9415795
Locus: 19p13.2
Gene Diseases
The ZNF699 NR1I2 Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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