ZNF599-SCN1B Fusion FISH Probe
The ZNF599-SCN1B Fusion FISH Probe is used to confirm a fusion of the ZNF599 and SCN1B genes. The fusion of the ZNF599 and SCN1B genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ZNF599-SCN1B-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ZNF599-SCN1B-20-RERE | 20 (40 μL) | 200 μL |
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| ZNF599-SCN1B-20-REOR | 20 (40 μL) | 200 μL |
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| ZNF599-SCN1B-20-REGO | 20 (40 μL) | 200 μL |
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| ZNF599-SCN1B-20-REGR | 20 (40 μL) | 200 μL |
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| ZNF599-SCN1B-20-REAQ | 20 (40 μL) | 200 μL |
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| ZNF599-SCN1B-20-ORRE | 20 (40 μL) | 200 μL |
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| ZNF599-SCN1B-20-OROR | 20 (40 μL) | 200 μL |
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| ZNF599-SCN1B-20-ORGO | 20 (40 μL) | 200 μL |
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| ZNF599-SCN1B-20-ORAQ | 20 (40 μL) | 200 μL |
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| ZNF599-SCN1B-20-GORE | 20 (40 μL) | 200 μL |
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| ZNF599-SCN1B-20-GOOR | 20 (40 μL) | 200 μL |
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| ZNF599-SCN1B-20-GOGO | 20 (40 μL) | 200 μL |
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| ZNF599-SCN1B-20-GOGR | 20 (40 μL) | 200 μL |
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| ZNF599-SCN1B-20-GOAQ | 20 (40 μL) | 200 μL |
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| ZNF599-SCN1B-20-GRRE | 20 (40 μL) | 200 μL |
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| ZNF599-SCN1B-20-GROR | 20 (40 μL) | 200 μL |
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| ZNF599-SCN1B-20-GRGO | 20 (40 μL) | 200 μL |
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| ZNF599-SCN1B-20-GRGR | 20 (40 μL) | 200 μL |
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| ZNF599-SCN1B-20-GRAQ | 20 (40 μL) | 200 μL |
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| ZNF599-SCN1B-20-AQRE | 20 (40 μL) | 200 μL |
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| ZNF599-SCN1B-20-AQOR | 20 (40 μL) | 200 μL |
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| ZNF599-SCN1B-20-AQGO | 20 (40 μL) | 200 μL |
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| ZNF599-SCN1B-20-AQGR | 20 (40 μL) | 200 μL |
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| ZNF599-SCN1B-20-AQAQ | 20 (40 μL) | 200 μL |
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SCN1B Gene Summary
Voltage-gated sodium channels are heteromeric proteins that function in the generation and propagation of action potentials in muscle and neuronal cells. They are composed of one alpha and two beta subunits, where the alpha subunit provides channel activity and the beta-1 subunit modulates the kinetics of channel inactivation. This gene encodes a sodium channel beta-1 subunit. Mutations in this gene result in generalized epilepsy with febrile seizures plus, Brugada syndrome 5, and defects in cardiac conduction. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2009]
Gene Name: Sodium Voltage-gated Channel Beta Subunit 1
Chromosome: CHR19: 35521591 -35531353
Locus: 19q13.11
ZNF599 Gene Summary
The Zinc Finger Protein 599 (ZNF599) gene is located on chr19 :35248978-35264134 at 19q13.11.
Gene Name: Zinc Finger Protein 599
Chromosome: CHR19: 35248978 -35264134
Locus: 19q13.11
Gene Diseases
The ZNF599 SCN1B Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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