ZNF586-AATF Fusion FISH Probe
The ZNF586-AATF Fusion FISH Probe is used to confirm a fusion of the ZNF586 and AATF genes. The fusion of the ZNF586 and AATF genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ZNF586-AATF-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ZNF586-AATF-20-RERE | 20 (40 μL) | 200 μL |
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| ZNF586-AATF-20-REOR | 20 (40 μL) | 200 μL |
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| ZNF586-AATF-20-REGO | 20 (40 μL) | 200 μL |
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| ZNF586-AATF-20-REGR | 20 (40 μL) | 200 μL |
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| ZNF586-AATF-20-REAQ | 20 (40 μL) | 200 μL |
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| ZNF586-AATF-20-ORRE | 20 (40 μL) | 200 μL |
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| ZNF586-AATF-20-OROR | 20 (40 μL) | 200 μL |
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| ZNF586-AATF-20-ORGO | 20 (40 μL) | 200 μL |
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| ZNF586-AATF-20-ORAQ | 20 (40 μL) | 200 μL |
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| ZNF586-AATF-20-GORE | 20 (40 μL) | 200 μL |
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| ZNF586-AATF-20-GOOR | 20 (40 μL) | 200 μL |
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| ZNF586-AATF-20-GOGO | 20 (40 μL) | 200 μL |
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| ZNF586-AATF-20-GOGR | 20 (40 μL) | 200 μL |
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| ZNF586-AATF-20-GOAQ | 20 (40 μL) | 200 μL |
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| ZNF586-AATF-20-GRRE | 20 (40 μL) | 200 μL |
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| ZNF586-AATF-20-GROR | 20 (40 μL) | 200 μL |
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| ZNF586-AATF-20-GRGO | 20 (40 μL) | 200 μL |
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| ZNF586-AATF-20-GRGR | 20 (40 μL) | 200 μL |
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| ZNF586-AATF-20-GRAQ | 20 (40 μL) | 200 μL |
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| ZNF586-AATF-20-AQRE | 20 (40 μL) | 200 μL |
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| ZNF586-AATF-20-AQOR | 20 (40 μL) | 200 μL |
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| ZNF586-AATF-20-AQGO | 20 (40 μL) | 200 μL |
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| ZNF586-AATF-20-AQGR | 20 (40 μL) | 200 μL |
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| ZNF586-AATF-20-AQAQ | 20 (40 μL) | 200 μL |
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AATF Gene Summary
The protein encoded by this gene was identified on the basis of its interaction with MAP3K12/DLK, a protein kinase known to be involved in the induction of cell apoptosis. This gene product contains a leucine zipper, which is a characteristic motif of transcription factors, and was shown to exhibit strong transactivation activity when fused to Gal4 DNA binding domain. Overexpression of this gene interfered with MAP3K12 induced apoptosis. [provided by RefSeq, Jul 2008]
Gene Name: Apoptosis Antagonizing Transcription Factor
Chromosome: CHR17: 35306174 -35414171
Locus: 17q12
ZNF586 Gene Summary
The Zinc Finger Protein 586 (ZNF586) gene is located on chr19 :58281019-58291984 at 19q13.43.
Gene Name: Zinc Finger Protein 586
Chromosome: CHR19: 58281019 -58291984
Locus: 19q13.43
Gene Diseases
The ZNF586 AATF Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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