ZNF507-FXYD1 Fusion FISH Probe
The ZNF507-FXYD1 Fusion FISH Probe is used to confirm a fusion of the ZNF507 and FXYD1 genes. The fusion of the ZNF507 and FXYD1 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ZNF507-FXYD1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ZNF507-FXYD1-20-RERE | 20 (40 μL) | 200 μL |
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| ZNF507-FXYD1-20-REOR | 20 (40 μL) | 200 μL |
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| ZNF507-FXYD1-20-REGO | 20 (40 μL) | 200 μL |
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| ZNF507-FXYD1-20-REGR | 20 (40 μL) | 200 μL |
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| ZNF507-FXYD1-20-REAQ | 20 (40 μL) | 200 μL |
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| ZNF507-FXYD1-20-ORRE | 20 (40 μL) | 200 μL |
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| ZNF507-FXYD1-20-OROR | 20 (40 μL) | 200 μL |
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| ZNF507-FXYD1-20-ORGO | 20 (40 μL) | 200 μL |
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| ZNF507-FXYD1-20-ORAQ | 20 (40 μL) | 200 μL |
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| ZNF507-FXYD1-20-GORE | 20 (40 μL) | 200 μL |
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| ZNF507-FXYD1-20-GOOR | 20 (40 μL) | 200 μL |
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| ZNF507-FXYD1-20-GOGO | 20 (40 μL) | 200 μL |
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| ZNF507-FXYD1-20-GOGR | 20 (40 μL) | 200 μL |
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| ZNF507-FXYD1-20-GOAQ | 20 (40 μL) | 200 μL |
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| ZNF507-FXYD1-20-GRRE | 20 (40 μL) | 200 μL |
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| ZNF507-FXYD1-20-GROR | 20 (40 μL) | 200 μL |
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| ZNF507-FXYD1-20-GRGO | 20 (40 μL) | 200 μL |
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| ZNF507-FXYD1-20-GRGR | 20 (40 μL) | 200 μL |
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| ZNF507-FXYD1-20-GRAQ | 20 (40 μL) | 200 μL |
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| ZNF507-FXYD1-20-AQRE | 20 (40 μL) | 200 μL |
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| ZNF507-FXYD1-20-AQOR | 20 (40 μL) | 200 μL |
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| ZNF507-FXYD1-20-AQGO | 20 (40 μL) | 200 μL |
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| ZNF507-FXYD1-20-AQGR | 20 (40 μL) | 200 μL |
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| ZNF507-FXYD1-20-AQAQ | 20 (40 μL) | 200 μL |
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FXYD1 Gene Summary
This gene encodes a member of a family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD and containing 7 invariant and 6 highly conserved amino acids. The approved human gene nomenclature for the family is FXYD-domain containing ion transport regulator. Mouse FXYD5 has been termed RIC (Related to Ion Channel). FXYD2, also known as the gamma subunit of the Na,K-ATPase, regulates the properties of that enzyme. FXYD1 (phospholemman), FXYD2 (gamma), FXYD3 (MAT-8), FXYD4 (CHIF), and FXYD5 (RIC) have been shown to induce channel activity in experimental expression systems. Transmembrane topology has been established for two family members (FXYD1 and FXYD2), with the N-terminus extracellular and the C-terminus on the cytoplasmic side of the membrane. The protein encoded by this gene is a plasma membrane substrate for several kinases, including protein kinase A, protein kinase C, NIMA kinase, and myotonic dystrophy kinase. It is thought to form an ion channel or regulate ion channel activity. Transcript variants with different 5' UTR sequences have been described in the literature. [provided by RefSeq, Jul 2008]
Gene Name: FXYD Domain Containing Ion Transport Regulator 1
Chromosome: CHR19: 35629731 -35633954
Locus: 19q13.12
ZNF507 Gene Summary
The Zinc Finger Protein 507 (ZNF507) gene is located on chr19 :32836513-32878573 at 19q13.11.
Gene Name: Zinc Finger Protein 507
Chromosome: CHR19: 32836513 -32878573
Locus: 19q13.11
Gene Diseases
The ZNF507 FXYD1 Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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