ZNF433-RFX1 Fusion FISH Probe
The ZNF433-RFX1 Fusion FISH Probe is used to confirm a fusion of the ZNF433 and RFX1 genes. The fusion of the ZNF433 and RFX1 genes has been associated with Brain Lower Grade Glioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ZNF433-RFX1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ZNF433-RFX1-20-RERE | 20 (40 μL) | 200 μL |
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| ZNF433-RFX1-20-REOR | 20 (40 μL) | 200 μL |
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| ZNF433-RFX1-20-REGO | 20 (40 μL) | 200 μL |
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| ZNF433-RFX1-20-REGR | 20 (40 μL) | 200 μL |
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| ZNF433-RFX1-20-REAQ | 20 (40 μL) | 200 μL |
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| ZNF433-RFX1-20-ORRE | 20 (40 μL) | 200 μL |
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| ZNF433-RFX1-20-OROR | 20 (40 μL) | 200 μL |
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| ZNF433-RFX1-20-ORGO | 20 (40 μL) | 200 μL |
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| ZNF433-RFX1-20-ORAQ | 20 (40 μL) | 200 μL |
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| ZNF433-RFX1-20-GORE | 20 (40 μL) | 200 μL |
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| ZNF433-RFX1-20-GOOR | 20 (40 μL) | 200 μL |
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| ZNF433-RFX1-20-GOGO | 20 (40 μL) | 200 μL |
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| ZNF433-RFX1-20-GOGR | 20 (40 μL) | 200 μL |
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| ZNF433-RFX1-20-GOAQ | 20 (40 μL) | 200 μL |
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| ZNF433-RFX1-20-GRRE | 20 (40 μL) | 200 μL |
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| ZNF433-RFX1-20-GROR | 20 (40 μL) | 200 μL |
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| ZNF433-RFX1-20-GRGO | 20 (40 μL) | 200 μL |
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| ZNF433-RFX1-20-GRGR | 20 (40 μL) | 200 μL |
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| ZNF433-RFX1-20-GRAQ | 20 (40 μL) | 200 μL |
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| ZNF433-RFX1-20-AQRE | 20 (40 μL) | 200 μL |
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| ZNF433-RFX1-20-AQOR | 20 (40 μL) | 200 μL |
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| ZNF433-RFX1-20-AQGO | 20 (40 μL) | 200 μL |
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| ZNF433-RFX1-20-AQGR | 20 (40 μL) | 200 μL |
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| ZNF433-RFX1-20-AQAQ | 20 (40 μL) | 200 μL |
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RFX1 Gene Summary
This gene encodes a member of the regulatory factor X (RFX) family of transcription factors, which are characterized by a winged-helix DNA-binding domain. The encoded transcription factor contains an N-terminal activation domain and a C-terminal repression domain, and may activate or repress target gene expression depending on cellular context. This transcription factor has been shown to regulate a wide variety of genes involved in immunity and cancer, including the MHC class II genes and genes that may be involved in cancer progression. This gene exhibits altered expression in glioblastoma and the autoimmune disease systemic lupus erythematosis (SLE). [provided by RefSeq, Jul 2016]
Gene Name: Regulatory Factor X1
Chromosome: CHR19: 14072341 -14117134
Locus: 19p13.12
ZNF433 Gene Summary
The Zinc Finger Protein 433 (ZNF433) gene is located on chr19 :12125531-12146525 at 19p13.2.
Gene Name: Zinc Finger Protein 433
Chromosome: CHR19: 12125531 -12146525
Locus: 19p13.2
Gene Diseases
The ZNF433 RFX1 Fusion has been associated with the following diseases:
| Disease Name |
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| Brain Lower Grade Glioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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