ZNF431-SIGLEC6 Fusion FISH Probe
The ZNF431-SIGLEC6 Fusion FISH Probe is used to confirm a fusion of the ZNF431 and SIGLEC6 genes. The fusion of the ZNF431 and SIGLEC6 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ZNF431-SIGLEC6-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ZNF431-SIGLEC6-20-RERE | 20 (40 μL) | 200 μL |
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| ZNF431-SIGLEC6-20-REOR | 20 (40 μL) | 200 μL |
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| ZNF431-SIGLEC6-20-REGO | 20 (40 μL) | 200 μL |
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| ZNF431-SIGLEC6-20-REGR | 20 (40 μL) | 200 μL |
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| ZNF431-SIGLEC6-20-REAQ | 20 (40 μL) | 200 μL |
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| ZNF431-SIGLEC6-20-ORRE | 20 (40 μL) | 200 μL |
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| ZNF431-SIGLEC6-20-OROR | 20 (40 μL) | 200 μL |
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| ZNF431-SIGLEC6-20-ORGO | 20 (40 μL) | 200 μL |
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| ZNF431-SIGLEC6-20-ORAQ | 20 (40 μL) | 200 μL |
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| ZNF431-SIGLEC6-20-GORE | 20 (40 μL) | 200 μL |
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| ZNF431-SIGLEC6-20-GOOR | 20 (40 μL) | 200 μL |
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| ZNF431-SIGLEC6-20-GOGO | 20 (40 μL) | 200 μL |
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| ZNF431-SIGLEC6-20-GOGR | 20 (40 μL) | 200 μL |
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| ZNF431-SIGLEC6-20-GOAQ | 20 (40 μL) | 200 μL |
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| ZNF431-SIGLEC6-20-GRRE | 20 (40 μL) | 200 μL |
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| ZNF431-SIGLEC6-20-GROR | 20 (40 μL) | 200 μL |
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| ZNF431-SIGLEC6-20-GRGO | 20 (40 μL) | 200 μL |
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| ZNF431-SIGLEC6-20-GRGR | 20 (40 μL) | 200 μL |
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| ZNF431-SIGLEC6-20-GRAQ | 20 (40 μL) | 200 μL |
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| ZNF431-SIGLEC6-20-AQRE | 20 (40 μL) | 200 μL |
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| ZNF431-SIGLEC6-20-AQOR | 20 (40 μL) | 200 μL |
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| ZNF431-SIGLEC6-20-AQGO | 20 (40 μL) | 200 μL |
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| ZNF431-SIGLEC6-20-AQGR | 20 (40 μL) | 200 μL |
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| ZNF431-SIGLEC6-20-AQAQ | 20 (40 μL) | 200 μL |
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SIGLEC6 Gene Summary
This gene encodes a member of the SIGLEC (sialic acid binding immunoglobulin-like lectin) family of proteins. The encoded transmembrane receptor binds sialyl-TN glycans and leptin. Placental expression of the encoded protein is upregulated in preeclampsia. [provided by RefSeq, Jul 2016]
Gene Name: Sialic Acid Binding Ig Like Lectin 6
Chromosome: CHR19: 52022783 -52035110
Locus: 19q13.41
ZNF431 Gene Summary
This gene encodes a member of the Krueppel C2H2-type zinc-finger family of proteins. The encoded protein may negatively regulate transcription of target genes, including the hedgehog signaling pathway receptor patched 1, by interacting with histone deacetylases. Mutations in this gene may be associated with non-syndromic facial clefting in human patients. [provided by RefSeq, Jul 2016]
Gene Name: Zinc Finger Protein 431
Chromosome: CHR19: 21324839 -21368805
Locus: 19p12
Gene Diseases
The ZNF431 SIGLEC6 Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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