ZNF398-TPK1 Fusion FISH Probe
The ZNF398-TPK1 Fusion FISH Probe is used to confirm a fusion of the ZNF398 and TPK1 genes. The fusion of the ZNF398 and TPK1 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ZNF398-TPK1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ZNF398-TPK1-20-RERE | 20 (40 μL) | 200 μL |
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| ZNF398-TPK1-20-REOR | 20 (40 μL) | 200 μL |
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| ZNF398-TPK1-20-REGO | 20 (40 μL) | 200 μL |
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| ZNF398-TPK1-20-REGR | 20 (40 μL) | 200 μL |
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| ZNF398-TPK1-20-REAQ | 20 (40 μL) | 200 μL |
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| ZNF398-TPK1-20-ORRE | 20 (40 μL) | 200 μL |
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| ZNF398-TPK1-20-OROR | 20 (40 μL) | 200 μL |
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| ZNF398-TPK1-20-ORGO | 20 (40 μL) | 200 μL |
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| ZNF398-TPK1-20-ORAQ | 20 (40 μL) | 200 μL |
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| ZNF398-TPK1-20-GORE | 20 (40 μL) | 200 μL |
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| ZNF398-TPK1-20-GOOR | 20 (40 μL) | 200 μL |
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| ZNF398-TPK1-20-GOGO | 20 (40 μL) | 200 μL |
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| ZNF398-TPK1-20-GOGR | 20 (40 μL) | 200 μL |
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| ZNF398-TPK1-20-GOAQ | 20 (40 μL) | 200 μL |
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| ZNF398-TPK1-20-GRRE | 20 (40 μL) | 200 μL |
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| ZNF398-TPK1-20-GROR | 20 (40 μL) | 200 μL |
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| ZNF398-TPK1-20-GRGO | 20 (40 μL) | 200 μL |
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| ZNF398-TPK1-20-GRGR | 20 (40 μL) | 200 μL |
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| ZNF398-TPK1-20-GRAQ | 20 (40 μL) | 200 μL |
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| ZNF398-TPK1-20-AQRE | 20 (40 μL) | 200 μL |
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| ZNF398-TPK1-20-AQOR | 20 (40 μL) | 200 μL |
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| ZNF398-TPK1-20-AQGO | 20 (40 μL) | 200 μL |
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| ZNF398-TPK1-20-AQGR | 20 (40 μL) | 200 μL |
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| ZNF398-TPK1-20-AQAQ | 20 (40 μL) | 200 μL |
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TPK1 Gene Summary
The protein encoded by this gene functions as a homodimer and catalyzes the conversion of thiamine to thiamine pyrophosphate, a cofactor for some enzymes of the glycolytic and energy production pathways. Defects in this gene are a cause of thiamine metabolism dysfunction syndrome-5. [provided by RefSeq, Apr 2017]
Gene Name: Thiamin Pyrophosphokinase 1
Chromosome: CHR7: 144149033 -144533146
Locus: 7q35
ZNF398 Gene Summary
This gene encodes a member of the Kruppel family of C2H2-type zinc-finger transcription factor proteins. The encoded protein acts as a transcriptional activator. Two transcript variants encoding distinct isoforms have been identified for this gene. Other transcript variants have been described, but their full length sequence has not been determined. [provided by RefSeq, Jul 2008]
Gene Name: Zinc Finger Protein 398
Chromosome: CHR7: 148823507 -148880118
Locus: 7q36.1
Gene Diseases
The ZNF398 TPK1 Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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