ZNF331-NLRP11 Fusion FISH Probe
The ZNF331-NLRP11 Fusion FISH Probe is used to confirm a fusion of the ZNF331 and NLRP11 genes. The fusion of the ZNF331 and NLRP11 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ZNF331-NLRP11-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ZNF331-NLRP11-20-RERE | 20 (40 μL) | 200 μL |
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| ZNF331-NLRP11-20-REOR | 20 (40 μL) | 200 μL |
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| ZNF331-NLRP11-20-REGO | 20 (40 μL) | 200 μL |
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| ZNF331-NLRP11-20-REGR | 20 (40 μL) | 200 μL |
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| ZNF331-NLRP11-20-REAQ | 20 (40 μL) | 200 μL |
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| ZNF331-NLRP11-20-ORRE | 20 (40 μL) | 200 μL |
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| ZNF331-NLRP11-20-OROR | 20 (40 μL) | 200 μL |
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| ZNF331-NLRP11-20-ORGO | 20 (40 μL) | 200 μL |
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| ZNF331-NLRP11-20-ORAQ | 20 (40 μL) | 200 μL |
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| ZNF331-NLRP11-20-GORE | 20 (40 μL) | 200 μL |
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| ZNF331-NLRP11-20-GOOR | 20 (40 μL) | 200 μL |
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| ZNF331-NLRP11-20-GOGO | 20 (40 μL) | 200 μL |
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| ZNF331-NLRP11-20-GOGR | 20 (40 μL) | 200 μL |
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| ZNF331-NLRP11-20-GOAQ | 20 (40 μL) | 200 μL |
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| ZNF331-NLRP11-20-GRRE | 20 (40 μL) | 200 μL |
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| ZNF331-NLRP11-20-GROR | 20 (40 μL) | 200 μL |
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| ZNF331-NLRP11-20-GRGO | 20 (40 μL) | 200 μL |
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| ZNF331-NLRP11-20-GRGR | 20 (40 μL) | 200 μL |
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| ZNF331-NLRP11-20-GRAQ | 20 (40 μL) | 200 μL |
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| ZNF331-NLRP11-20-AQRE | 20 (40 μL) | 200 μL |
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| ZNF331-NLRP11-20-AQOR | 20 (40 μL) | 200 μL |
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| ZNF331-NLRP11-20-AQGO | 20 (40 μL) | 200 μL |
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| ZNF331-NLRP11-20-AQGR | 20 (40 μL) | 200 μL |
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| ZNF331-NLRP11-20-AQAQ | 20 (40 μL) | 200 μL |
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ZNF331 Gene Summary
This gene encodes a zinc finger protein containing a KRAB (Kruppel-associated box) domain found in transcriptional repressors. This gene may be methylated and silenced in cancer cells. This gene is located within a differentially methylated region (DMR) and shows allele-specific expression in placenta. Alternative splicing and the use of alternative promoters results in multiple transcript variants encoding the same protein. [provided by RefSeq, Nov 2015]
Gene Name: Zinc Finger Protein 331
Chromosome: CHR19: 54024176 -54083523
Locus: 19q13.42
NLRP11 Gene Summary
This gene is a member of the the NOD-like receptor protein (NLRP) gene family and encodes a protein with an N-terminal pyrin death (PYD) domain and nucleoside triphosphate hydrolase (NACHT) domain and a C-terminal leucine-rich repeats (LRR) region. This gene has been shown to regulate caspases in the proinflammatory signal transduction pathway and, based on studies of other members of the NLRP gene family with similar domain structure, is predicted to form part of the multiprotein inflammasome complex. Alternative splicing produces multiple transcript variants encoding distince isoforms. [provided by RefSeq, May 2017]
Gene Name: NLR Family Pyrin Domain Containing 11
Chromosome: CHR19: 56296762 -56348128
Locus: 19q13.42-q13.43
Gene Diseases
The ZNF331 NLRP11 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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