ZNF318-CD2AP Fusion FISH Probe
The ZNF318-CD2AP Fusion FISH Probe is used to confirm a fusion of the ZNF318 and CD2AP genes. The fusion of the ZNF318 and CD2AP genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ZNF318-CD2AP-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ZNF318-CD2AP-20-RERE | 20 (40 μL) | 200 μL |
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| ZNF318-CD2AP-20-REOR | 20 (40 μL) | 200 μL |
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| ZNF318-CD2AP-20-REGO | 20 (40 μL) | 200 μL |
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| ZNF318-CD2AP-20-REGR | 20 (40 μL) | 200 μL |
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| ZNF318-CD2AP-20-REAQ | 20 (40 μL) | 200 μL |
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| ZNF318-CD2AP-20-ORRE | 20 (40 μL) | 200 μL |
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| ZNF318-CD2AP-20-OROR | 20 (40 μL) | 200 μL |
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| ZNF318-CD2AP-20-ORGO | 20 (40 μL) | 200 μL |
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| ZNF318-CD2AP-20-ORAQ | 20 (40 μL) | 200 μL |
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| ZNF318-CD2AP-20-GORE | 20 (40 μL) | 200 μL |
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| ZNF318-CD2AP-20-GOOR | 20 (40 μL) | 200 μL |
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| ZNF318-CD2AP-20-GOGO | 20 (40 μL) | 200 μL |
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| ZNF318-CD2AP-20-GOGR | 20 (40 μL) | 200 μL |
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| ZNF318-CD2AP-20-GOAQ | 20 (40 μL) | 200 μL |
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| ZNF318-CD2AP-20-GRRE | 20 (40 μL) | 200 μL |
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| ZNF318-CD2AP-20-GROR | 20 (40 μL) | 200 μL |
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| ZNF318-CD2AP-20-GRGO | 20 (40 μL) | 200 μL |
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| ZNF318-CD2AP-20-GRGR | 20 (40 μL) | 200 μL |
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| ZNF318-CD2AP-20-GRAQ | 20 (40 μL) | 200 μL |
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| ZNF318-CD2AP-20-AQRE | 20 (40 μL) | 200 μL |
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| ZNF318-CD2AP-20-AQOR | 20 (40 μL) | 200 μL |
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| ZNF318-CD2AP-20-AQGO | 20 (40 μL) | 200 μL |
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| ZNF318-CD2AP-20-AQGR | 20 (40 μL) | 200 μL |
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| ZNF318-CD2AP-20-AQAQ | 20 (40 μL) | 200 μL |
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CD2AP Gene Summary
This gene encodes a scaffolding molecule that regulates the actin cytoskeleton. The protein directly interacts with filamentous actin and a variety of cell membrane proteins through multiple actin binding sites, SH3 domains, and a proline-rich region containing binding sites for SH3 domains. The cytoplasmic protein localizes to membrane ruffles, lipid rafts, and the leading edges of cells. It is implicated in dynamic actin remodeling and membrane trafficking that occurs during receptor endocytosis and cytokinesis. Haploinsufficiency of this gene is implicated in susceptibility to glomerular disease. [provided by RefSeq, Jul 2008]
Gene Name: CD2 Associated Protein
Chromosome: CHR6: 47445524 -47594996
Locus: 6p12.3
ZNF318 Gene Summary
The Zinc Finger Protein 318 (ZNF318) gene is located on chr6 :43303807-43337181 at 6p21.1.
Gene Name: Zinc Finger Protein 318
Chromosome: CHR6: 43303807 -43337181
Locus: 6p21.1
Gene Diseases
The ZNF318 CD2AP Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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