ZNF148-AGXT Fusion FISH Probe
The ZNF148-AGXT Fusion FISH Probe is used to confirm a fusion of the ZNF148 and AGXT genes. The fusion of the ZNF148 and AGXT genes has been associated with Uterine Corpus Endometrial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ZNF148-AGXT-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ZNF148-AGXT-20-RERE | 20 (40 μL) | 200 μL |
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| ZNF148-AGXT-20-REOR | 20 (40 μL) | 200 μL |
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| ZNF148-AGXT-20-REGO | 20 (40 μL) | 200 μL |
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| ZNF148-AGXT-20-REGR | 20 (40 μL) | 200 μL |
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| ZNF148-AGXT-20-REAQ | 20 (40 μL) | 200 μL |
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| ZNF148-AGXT-20-ORRE | 20 (40 μL) | 200 μL |
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| ZNF148-AGXT-20-OROR | 20 (40 μL) | 200 μL |
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| ZNF148-AGXT-20-ORGO | 20 (40 μL) | 200 μL |
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| ZNF148-AGXT-20-ORAQ | 20 (40 μL) | 200 μL |
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| ZNF148-AGXT-20-GORE | 20 (40 μL) | 200 μL |
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| ZNF148-AGXT-20-GOOR | 20 (40 μL) | 200 μL |
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| ZNF148-AGXT-20-GOGO | 20 (40 μL) | 200 μL |
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| ZNF148-AGXT-20-GOGR | 20 (40 μL) | 200 μL |
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| ZNF148-AGXT-20-GOAQ | 20 (40 μL) | 200 μL |
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| ZNF148-AGXT-20-GRRE | 20 (40 μL) | 200 μL |
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| ZNF148-AGXT-20-GROR | 20 (40 μL) | 200 μL |
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| ZNF148-AGXT-20-GRGO | 20 (40 μL) | 200 μL |
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| ZNF148-AGXT-20-GRGR | 20 (40 μL) | 200 μL |
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| ZNF148-AGXT-20-GRAQ | 20 (40 μL) | 200 μL |
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| ZNF148-AGXT-20-AQRE | 20 (40 μL) | 200 μL |
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| ZNF148-AGXT-20-AQOR | 20 (40 μL) | 200 μL |
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| ZNF148-AGXT-20-AQGO | 20 (40 μL) | 200 μL |
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| ZNF148-AGXT-20-AQGR | 20 (40 μL) | 200 μL |
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| ZNF148-AGXT-20-AQAQ | 20 (40 μL) | 200 μL |
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AGXT Gene Summary
This gene is expressed only in the liver and the encoded protein is localized mostly in the peroxisomes, where it is involved in glyoxylate detoxification. Mutations in this gene, some of which alter subcellular targetting, have been associated with type I primary hyperoxaluria. [provided by RefSeq, Jul 2008]
Gene Name: Alanine-glyoxylate Aminotransferase
Chromosome: CHR2: 241808161 -241818536
Locus: 2q37.3
ZNF148 Gene Summary
The protein encoded by this gene is a member of the Kruppel family of zinc finger DNA binding proteins. The encoded protein activates transcription of the T-cell receptor and intestinal alkaline phosphatase genes but represses transcription of the ornithine decarboxylase, vimentin, gastrin, stomelysin, and enolase genes. Increased expression of this gene results in decreased patient survival rates from colorectal cancer, while mutations in this gene have been associated with global developmental delay, hypoplastic corpus callosum, and dysmorphic facies. [provided by RefSeq, Feb 2017]
Gene Name: Zinc Finger Protein 148
Chromosome: CHR3: 124944512 -125094198
Locus: 3q21.2
Gene Diseases
The ZNF148 AGXT Fusion has been associated with the following diseases:
| Disease Name |
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| Uterine Corpus Endometrial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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