ZNF142-POLR1B Fusion FISH Probe
The ZNF142-POLR1B Fusion FISH Probe is used to confirm a fusion of the ZNF142 and POLR1B genes. The fusion of the ZNF142 and POLR1B genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ZNF142-POLR1B-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ZNF142-POLR1B-20-RERE | 20 (40 μL) | 200 μL |
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| ZNF142-POLR1B-20-REOR | 20 (40 μL) | 200 μL |
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| ZNF142-POLR1B-20-REGO | 20 (40 μL) | 200 μL |
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| ZNF142-POLR1B-20-REGR | 20 (40 μL) | 200 μL |
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| ZNF142-POLR1B-20-REAQ | 20 (40 μL) | 200 μL |
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| ZNF142-POLR1B-20-ORRE | 20 (40 μL) | 200 μL |
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| ZNF142-POLR1B-20-OROR | 20 (40 μL) | 200 μL |
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| ZNF142-POLR1B-20-ORGO | 20 (40 μL) | 200 μL |
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| ZNF142-POLR1B-20-ORAQ | 20 (40 μL) | 200 μL |
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| ZNF142-POLR1B-20-GORE | 20 (40 μL) | 200 μL |
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| ZNF142-POLR1B-20-GOOR | 20 (40 μL) | 200 μL |
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| ZNF142-POLR1B-20-GOGO | 20 (40 μL) | 200 μL |
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| ZNF142-POLR1B-20-GOGR | 20 (40 μL) | 200 μL |
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| ZNF142-POLR1B-20-GOAQ | 20 (40 μL) | 200 μL |
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| ZNF142-POLR1B-20-GRRE | 20 (40 μL) | 200 μL |
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| ZNF142-POLR1B-20-GROR | 20 (40 μL) | 200 μL |
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| ZNF142-POLR1B-20-GRGO | 20 (40 μL) | 200 μL |
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| ZNF142-POLR1B-20-GRGR | 20 (40 μL) | 200 μL |
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| ZNF142-POLR1B-20-GRAQ | 20 (40 μL) | 200 μL |
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| ZNF142-POLR1B-20-AQRE | 20 (40 μL) | 200 μL |
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| ZNF142-POLR1B-20-AQOR | 20 (40 μL) | 200 μL |
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| ZNF142-POLR1B-20-AQGO | 20 (40 μL) | 200 μL |
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| ZNF142-POLR1B-20-AQGR | 20 (40 μL) | 200 μL |
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| ZNF142-POLR1B-20-AQAQ | 20 (40 μL) | 200 μL |
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ZNF142 Gene Summary
The protein encoded by this gene belongs to the Kruppel family of C2H2-type zinc finger proteins. It contains 31 C2H2-type zinc fingers and may be involved in transcriptional regulation. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2013]
Gene Name: Zinc Finger Protein 142
Chromosome: CHR2: 219502639 -219524261
Locus: 2q35
POLR1B Gene Summary
Eukaryotic RNA polymerase I (pol I) is responsible for the transcription of ribosomal RNA (rRNA) genes and production of rRNA, the primary component of ribosomes. Pol I is a multisubunit enzyme composed of 6 to 14 polypeptides, depending on the species. Most of the mass of the pol I complex derives from the 2 largest subunits, Rpa1 and Rpa2 in yeast. POLR1B is homologous to Rpa2 (Seither and Grummt, 1996 [PubMed 8921381]).[supplied by OMIM, Mar 2008]
Gene Name: RNA Polymerase I Subunit B
Chromosome: CHR2: 113299491 -113334727
Locus: 2q14.1
Gene Diseases
The ZNF142 POLR1B Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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