ZMYND11-PCDH15 Fusion FISH Probe
The ZMYND11-PCDH15 Fusion FISH Probe is used to confirm a fusion of the ZMYND11 and PCDH15 genes. The fusion of the ZMYND11 and PCDH15 genes has been associated with Stomach Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ZMYND11-PCDH15-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ZMYND11-PCDH15-20-RERE | 20 (40 μL) | 200 μL |
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| ZMYND11-PCDH15-20-REOR | 20 (40 μL) | 200 μL |
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| ZMYND11-PCDH15-20-REGO | 20 (40 μL) | 200 μL |
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| ZMYND11-PCDH15-20-REGR | 20 (40 μL) | 200 μL |
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| ZMYND11-PCDH15-20-REAQ | 20 (40 μL) | 200 μL |
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| ZMYND11-PCDH15-20-ORRE | 20 (40 μL) | 200 μL |
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| ZMYND11-PCDH15-20-OROR | 20 (40 μL) | 200 μL |
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| ZMYND11-PCDH15-20-ORGO | 20 (40 μL) | 200 μL |
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| ZMYND11-PCDH15-20-ORAQ | 20 (40 μL) | 200 μL |
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| ZMYND11-PCDH15-20-GORE | 20 (40 μL) | 200 μL |
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| ZMYND11-PCDH15-20-GOOR | 20 (40 μL) | 200 μL |
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| ZMYND11-PCDH15-20-GOGO | 20 (40 μL) | 200 μL |
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| ZMYND11-PCDH15-20-GOGR | 20 (40 μL) | 200 μL |
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| ZMYND11-PCDH15-20-GOAQ | 20 (40 μL) | 200 μL |
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| ZMYND11-PCDH15-20-GRRE | 20 (40 μL) | 200 μL |
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| ZMYND11-PCDH15-20-GROR | 20 (40 μL) | 200 μL |
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| ZMYND11-PCDH15-20-GRGO | 20 (40 μL) | 200 μL |
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| ZMYND11-PCDH15-20-GRGR | 20 (40 μL) | 200 μL |
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| ZMYND11-PCDH15-20-GRAQ | 20 (40 μL) | 200 μL |
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| ZMYND11-PCDH15-20-AQRE | 20 (40 μL) | 200 μL |
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| ZMYND11-PCDH15-20-AQOR | 20 (40 μL) | 200 μL |
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| ZMYND11-PCDH15-20-AQGO | 20 (40 μL) | 200 μL |
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| ZMYND11-PCDH15-20-AQGR | 20 (40 μL) | 200 μL |
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| ZMYND11-PCDH15-20-AQAQ | 20 (40 μL) | 200 μL |
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ZMYND11 Gene Summary
The protein encoded by this gene was first identified by its ability to bind the adenovirus E1A protein. The protein localizes to the nucleus. It functions as a transcriptional repressor, and expression of E1A inhibits this repression. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Gene Name: Zinc Finger MYND-type Containing 11
Chromosome: CHR10: 180404 -300577
Locus: 10p15.3
PCDH15 Gene Summary
This gene is a member of the cadherin superfamily. Family members encode integral membrane proteins that mediate calcium-dependent cell-cell adhesion. It plays an essential role in maintenance of normal retinal and cochlear function. Mutations in this gene result in hearing loss and Usher Syndrome Type IF (USH1F). Extensive alternative splicing resulting in multiple isoforms has been observed in the mouse ortholog. Similar alternatively spliced transcripts are inferred to occur in human, and additional variants are likely to occur. [provided by RefSeq, Dec 2008]
Gene Name: Protocadherin Related 15
Chromosome: CHR10: 55562532 -56561051
Locus: 10q21.1
Gene Diseases
The ZMYND11 PCDH15 Fusion has been associated with the following diseases:
| Disease Name |
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| Stomach Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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