ZMYM2-DMRT2 Fusion FISH Probe
The ZMYM2-DMRT2 Fusion FISH Probe is used to confirm a fusion of the ZMYM2 and DMRT2 genes. The fusion of the ZMYM2 and DMRT2 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ZMYM2-DMRT2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ZMYM2-DMRT2-20-RERE | 20 (40 μL) | 200 μL |
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| ZMYM2-DMRT2-20-REOR | 20 (40 μL) | 200 μL |
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| ZMYM2-DMRT2-20-REGO | 20 (40 μL) | 200 μL |
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| ZMYM2-DMRT2-20-REGR | 20 (40 μL) | 200 μL |
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| ZMYM2-DMRT2-20-REAQ | 20 (40 μL) | 200 μL |
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| ZMYM2-DMRT2-20-ORRE | 20 (40 μL) | 200 μL |
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| ZMYM2-DMRT2-20-OROR | 20 (40 μL) | 200 μL |
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| ZMYM2-DMRT2-20-ORGO | 20 (40 μL) | 200 μL |
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| ZMYM2-DMRT2-20-ORAQ | 20 (40 μL) | 200 μL |
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| ZMYM2-DMRT2-20-GORE | 20 (40 μL) | 200 μL |
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| ZMYM2-DMRT2-20-GOOR | 20 (40 μL) | 200 μL |
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| ZMYM2-DMRT2-20-GOGO | 20 (40 μL) | 200 μL |
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| ZMYM2-DMRT2-20-GOGR | 20 (40 μL) | 200 μL |
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| ZMYM2-DMRT2-20-GOAQ | 20 (40 μL) | 200 μL |
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| ZMYM2-DMRT2-20-GRRE | 20 (40 μL) | 200 μL |
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| ZMYM2-DMRT2-20-GROR | 20 (40 μL) | 200 μL |
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| ZMYM2-DMRT2-20-GRGO | 20 (40 μL) | 200 μL |
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| ZMYM2-DMRT2-20-GRGR | 20 (40 μL) | 200 μL |
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| ZMYM2-DMRT2-20-GRAQ | 20 (40 μL) | 200 μL |
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| ZMYM2-DMRT2-20-AQRE | 20 (40 μL) | 200 μL |
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| ZMYM2-DMRT2-20-AQOR | 20 (40 μL) | 200 μL |
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| ZMYM2-DMRT2-20-AQGO | 20 (40 μL) | 200 μL |
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| ZMYM2-DMRT2-20-AQGR | 20 (40 μL) | 200 μL |
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| ZMYM2-DMRT2-20-AQAQ | 20 (40 μL) | 200 μL |
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ZMYM2 Gene Summary
The protein encoded by this gene is a zinc finger protein that may act as a transcription factor. The encoded protein may be part of a BHC histone deacetylase complex. Translocation of this gene with the fibroblast growth factor receptor-1 gene (FGFR1) results in a fusion gene, which may be a cause of stem cell leukemia lymphoma syndrome (SCLL). Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2010]
Gene Name: Zinc Finger MYM-type Containing 2
Chromosome: CHR13: 20532809 -20665968
Locus: 13q12.11
DMRT2 Gene Summary
The protein encoded by this gene belongs to the DMRT gene family, sharing a DM DNA-binding domain with Drosophila 'doublesex' (dsx) and C. elegans mab3, genes involved in sex determination in these organisms. Also, this gene is located in a region of the human genome (chromosome 9p24.3) associated with gonadal dysgenesis and XY sex reversal. Hence this gene is one of the candidates for sex-determining gene(s) on chr 9. [provided by RefSeq, Apr 2010]
Gene Name: Doublesex And Mab-3 Related Transcription Factor 2
Chromosome: CHR9: 1050345 -1057554
Locus: 9p24.3
Gene Diseases
The ZMYM2 DMRT2 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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