ZMPSTE24-TMCO2 Fusion FISH Probe
The ZMPSTE24-TMCO2 Fusion FISH Probe is used to confirm a fusion of the ZMPSTE24 and TMCO2 genes. The fusion of the ZMPSTE24 and TMCO2 genes has been associated with Colon Adenocarcinoma, and Uterine Corpus Endometrial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ZMPSTE24-TMCO2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ZMPSTE24-TMCO2-20-RERE | 20 (40 μL) | 200 μL |
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| ZMPSTE24-TMCO2-20-REOR | 20 (40 μL) | 200 μL |
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| ZMPSTE24-TMCO2-20-REGO | 20 (40 μL) | 200 μL |
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| ZMPSTE24-TMCO2-20-REGR | 20 (40 μL) | 200 μL |
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| ZMPSTE24-TMCO2-20-REAQ | 20 (40 μL) | 200 μL |
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| ZMPSTE24-TMCO2-20-ORRE | 20 (40 μL) | 200 μL |
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| ZMPSTE24-TMCO2-20-OROR | 20 (40 μL) | 200 μL |
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| ZMPSTE24-TMCO2-20-ORGO | 20 (40 μL) | 200 μL |
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| ZMPSTE24-TMCO2-20-ORAQ | 20 (40 μL) | 200 μL |
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| ZMPSTE24-TMCO2-20-GORE | 20 (40 μL) | 200 μL |
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| ZMPSTE24-TMCO2-20-GOOR | 20 (40 μL) | 200 μL |
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| ZMPSTE24-TMCO2-20-GOGO | 20 (40 μL) | 200 μL |
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| ZMPSTE24-TMCO2-20-GOGR | 20 (40 μL) | 200 μL |
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| ZMPSTE24-TMCO2-20-GOAQ | 20 (40 μL) | 200 μL |
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| ZMPSTE24-TMCO2-20-GRRE | 20 (40 μL) | 200 μL |
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| ZMPSTE24-TMCO2-20-GROR | 20 (40 μL) | 200 μL |
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| ZMPSTE24-TMCO2-20-GRGO | 20 (40 μL) | 200 μL |
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| ZMPSTE24-TMCO2-20-GRGR | 20 (40 μL) | 200 μL |
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| ZMPSTE24-TMCO2-20-GRAQ | 20 (40 μL) | 200 μL |
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| ZMPSTE24-TMCO2-20-AQRE | 20 (40 μL) | 200 μL |
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| ZMPSTE24-TMCO2-20-AQOR | 20 (40 μL) | 200 μL |
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| ZMPSTE24-TMCO2-20-AQGO | 20 (40 μL) | 200 μL |
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| ZMPSTE24-TMCO2-20-AQGR | 20 (40 μL) | 200 μL |
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| ZMPSTE24-TMCO2-20-AQAQ | 20 (40 μL) | 200 μL |
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ZMPSTE24 Gene Summary
This gene encodes a member of the peptidase M48A family. The encoded protein is a zinc metalloproteinase involved in the two step post-translational proteolytic cleavage of carboxy terminal residues of farnesylated prelamin A to form mature lamin A. Mutations in this gene have been associated with mandibuloacral dysplasia and restrictive dermopathy. [provided by RefSeq, Jul 2008]
Gene Name: Zinc Metallopeptidase STE24
Chromosome: CHR1: 40723732 -40759856
Locus: 1p34.2
TMCO2 Gene Summary
The Transmembrane And Coiled-coil Domains 2 (TMCO2) gene is located on chr1 :40713572-40717365 at 1p34.2.
Gene Name: Transmembrane And Coiled-coil Domains 2
Chromosome: CHR1: 40713572 -40717365
Locus: 1p34.2
Gene Diseases
The ZMPSTE24 TMCO2 Fusion has been associated with the following diseases:
| Disease Name |
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| Colon Adenocarcinoma |
| Uterine Corpus Endometrial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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