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ZMIZ1-CHST3 Fusion FISH Probe

The ZMIZ1-CHST3 Fusion FISH Probe is used to confirm a fusion of the ZMIZ1 and CHST3 genes. The fusion of the ZMIZ1 and CHST3 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
ZMIZ1-CHST3-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
ZMIZ1-CHST3-20-RERE 20 (40 μL) 200 μL
ZMIZ1-CHST3-20-REOR 20 (40 μL) 200 μL
ZMIZ1-CHST3-20-REGO 20 (40 μL) 200 μL
ZMIZ1-CHST3-20-REGR 20 (40 μL) 200 μL
ZMIZ1-CHST3-20-REAQ 20 (40 μL) 200 μL
ZMIZ1-CHST3-20-ORRE 20 (40 μL) 200 μL
ZMIZ1-CHST3-20-OROR 20 (40 μL) 200 μL
ZMIZ1-CHST3-20-ORGO 20 (40 μL) 200 μL
ZMIZ1-CHST3-20-ORAQ 20 (40 μL) 200 μL
ZMIZ1-CHST3-20-GORE 20 (40 μL) 200 μL
ZMIZ1-CHST3-20-GOOR 20 (40 μL) 200 μL
ZMIZ1-CHST3-20-GOGO 20 (40 μL) 200 μL
ZMIZ1-CHST3-20-GOGR 20 (40 μL) 200 μL
ZMIZ1-CHST3-20-GOAQ 20 (40 μL) 200 μL
ZMIZ1-CHST3-20-GRRE 20 (40 μL) 200 μL
ZMIZ1-CHST3-20-GROR 20 (40 μL) 200 μL
ZMIZ1-CHST3-20-GRGO 20 (40 μL) 200 μL
ZMIZ1-CHST3-20-GRGR 20 (40 μL) 200 μL
ZMIZ1-CHST3-20-GRAQ 20 (40 μL) 200 μL
ZMIZ1-CHST3-20-AQRE 20 (40 μL) 200 μL
ZMIZ1-CHST3-20-AQOR 20 (40 μL) 200 μL
ZMIZ1-CHST3-20-AQGO 20 (40 μL) 200 μL
ZMIZ1-CHST3-20-AQGR 20 (40 μL) 200 μL
ZMIZ1-CHST3-20-AQAQ 20 (40 μL) 200 μL

CHST3 Gene Summary

This gene encodes an enzyme which catalyzes the sulfation of chondroitin, a proteoglycan found in the extracellular matrix and most cells which is involved in cell migration and differentiation. Mutations in this gene are associated with spondylepiphyseal dysplasia and humerospinal dysostosis. [provided by RefSeq, Mar 2009]

Gene Name: Carbohydrate Sulfotransferase 3

Chromosome: CHR10: 73724119 -73773322

Locus: 10q22.1

ZMIZ1 Gene Summary

This gene encodes a member of the PIAS (protein inhibitor of activated STAT) family of proteins. The encoded protein regulates the activity of various transcription factors, including the androgen receptor, Smad3/4, and p53. The encoded protein may also play a role in sumoylation. A translocation between this locus on chromosome 10 and the protein tyrosine kinase ABL1 locus on chromosome 9 has been associated with acute lymphoblastic leukemia. [provided by RefSeq, Mar 2010]

Gene Name: Zinc Finger MIZ-type Containing 1

Chromosome: CHR10: 80828791 -81076285

Locus: 10q22.3

Gene Diseases

The ZMIZ1 CHST3 Fusion has been associated with the following diseases:

Disease Name
Sarcoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.