ZMIZ1-CHST3 Fusion FISH Probe
The ZMIZ1-CHST3 Fusion FISH Probe is used to confirm a fusion of the ZMIZ1 and CHST3 genes. The fusion of the ZMIZ1 and CHST3 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ZMIZ1-CHST3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ZMIZ1-CHST3-20-RERE | 20 (40 μL) | 200 μL |
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| ZMIZ1-CHST3-20-REOR | 20 (40 μL) | 200 μL |
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| ZMIZ1-CHST3-20-REGO | 20 (40 μL) | 200 μL |
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| ZMIZ1-CHST3-20-REGR | 20 (40 μL) | 200 μL |
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| ZMIZ1-CHST3-20-REAQ | 20 (40 μL) | 200 μL |
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| ZMIZ1-CHST3-20-ORRE | 20 (40 μL) | 200 μL |
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| ZMIZ1-CHST3-20-OROR | 20 (40 μL) | 200 μL |
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| ZMIZ1-CHST3-20-ORGO | 20 (40 μL) | 200 μL |
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| ZMIZ1-CHST3-20-ORAQ | 20 (40 μL) | 200 μL |
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| ZMIZ1-CHST3-20-GORE | 20 (40 μL) | 200 μL |
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| ZMIZ1-CHST3-20-GOOR | 20 (40 μL) | 200 μL |
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| ZMIZ1-CHST3-20-GOGO | 20 (40 μL) | 200 μL |
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| ZMIZ1-CHST3-20-GOGR | 20 (40 μL) | 200 μL |
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| ZMIZ1-CHST3-20-GOAQ | 20 (40 μL) | 200 μL |
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| ZMIZ1-CHST3-20-GRRE | 20 (40 μL) | 200 μL |
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| ZMIZ1-CHST3-20-GROR | 20 (40 μL) | 200 μL |
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| ZMIZ1-CHST3-20-GRGO | 20 (40 μL) | 200 μL |
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| ZMIZ1-CHST3-20-GRGR | 20 (40 μL) | 200 μL |
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| ZMIZ1-CHST3-20-GRAQ | 20 (40 μL) | 200 μL |
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| ZMIZ1-CHST3-20-AQRE | 20 (40 μL) | 200 μL |
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| ZMIZ1-CHST3-20-AQOR | 20 (40 μL) | 200 μL |
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| ZMIZ1-CHST3-20-AQGO | 20 (40 μL) | 200 μL |
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| ZMIZ1-CHST3-20-AQGR | 20 (40 μL) | 200 μL |
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| ZMIZ1-CHST3-20-AQAQ | 20 (40 μL) | 200 μL |
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CHST3 Gene Summary
This gene encodes an enzyme which catalyzes the sulfation of chondroitin, a proteoglycan found in the extracellular matrix and most cells which is involved in cell migration and differentiation. Mutations in this gene are associated with spondylepiphyseal dysplasia and humerospinal dysostosis. [provided by RefSeq, Mar 2009]
Gene Name: Carbohydrate Sulfotransferase 3
Chromosome: CHR10: 73724119 -73773322
Locus: 10q22.1
ZMIZ1 Gene Summary
This gene encodes a member of the PIAS (protein inhibitor of activated STAT) family of proteins. The encoded protein regulates the activity of various transcription factors, including the androgen receptor, Smad3/4, and p53. The encoded protein may also play a role in sumoylation. A translocation between this locus on chromosome 10 and the protein tyrosine kinase ABL1 locus on chromosome 9 has been associated with acute lymphoblastic leukemia. [provided by RefSeq, Mar 2010]
Gene Name: Zinc Finger MIZ-type Containing 1
Chromosome: CHR10: 80828791 -81076285
Locus: 10q22.3
Gene Diseases
The ZMIZ1 CHST3 Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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