ZMIZ1-ADK Fusion FISH Probe
The ZMIZ1-ADK Fusion FISH Probe is used to confirm a fusion of the ZMIZ1 and ADK genes. The fusion of the ZMIZ1 and ADK genes has been associated with Uterine Carcinosarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ZMIZ1-ADK-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ZMIZ1-ADK-20-RERE | 20 (40 μL) | 200 μL |
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| ZMIZ1-ADK-20-REOR | 20 (40 μL) | 200 μL |
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| ZMIZ1-ADK-20-REGO | 20 (40 μL) | 200 μL |
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| ZMIZ1-ADK-20-REGR | 20 (40 μL) | 200 μL |
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| ZMIZ1-ADK-20-REAQ | 20 (40 μL) | 200 μL |
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| ZMIZ1-ADK-20-ORRE | 20 (40 μL) | 200 μL |
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| ZMIZ1-ADK-20-OROR | 20 (40 μL) | 200 μL |
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| ZMIZ1-ADK-20-ORGO | 20 (40 μL) | 200 μL |
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| ZMIZ1-ADK-20-ORAQ | 20 (40 μL) | 200 μL |
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| ZMIZ1-ADK-20-GORE | 20 (40 μL) | 200 μL |
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| ZMIZ1-ADK-20-GOOR | 20 (40 μL) | 200 μL |
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| ZMIZ1-ADK-20-GOGO | 20 (40 μL) | 200 μL |
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| ZMIZ1-ADK-20-GOGR | 20 (40 μL) | 200 μL |
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| ZMIZ1-ADK-20-GOAQ | 20 (40 μL) | 200 μL |
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| ZMIZ1-ADK-20-GRRE | 20 (40 μL) | 200 μL |
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| ZMIZ1-ADK-20-GROR | 20 (40 μL) | 200 μL |
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| ZMIZ1-ADK-20-GRGO | 20 (40 μL) | 200 μL |
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| ZMIZ1-ADK-20-GRGR | 20 (40 μL) | 200 μL |
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| ZMIZ1-ADK-20-GRAQ | 20 (40 μL) | 200 μL |
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| ZMIZ1-ADK-20-AQRE | 20 (40 μL) | 200 μL |
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| ZMIZ1-ADK-20-AQOR | 20 (40 μL) | 200 μL |
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| ZMIZ1-ADK-20-AQGO | 20 (40 μL) | 200 μL |
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| ZMIZ1-ADK-20-AQGR | 20 (40 μL) | 200 μL |
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| ZMIZ1-ADK-20-AQAQ | 20 (40 μL) | 200 μL |
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ADK Gene Summary
This gene an enzyme which catalyzes the transfer of the gamma-phosphate from ATP to adenosine, thereby serving as a regulator of concentrations of both extracellular adenosine and intracellular adenine nucleotides. Adenosine has widespread effects on the cardiovascular, nervous, respiratory, and immune systems and inhibitors of the enzyme could play an important pharmacological role in increasing intravascular adenosine concentrations and acting as anti-inflammatory agents. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2011]
Gene Name: Adenosine Kinase
Chromosome: CHR10: 75910942 -76469061
Locus: 10q11-q24
ZMIZ1 Gene Summary
This gene encodes a member of the PIAS (protein inhibitor of activated STAT) family of proteins. The encoded protein regulates the activity of various transcription factors, including the androgen receptor, Smad3/4, and p53. The encoded protein may also play a role in sumoylation. A translocation between this locus on chromosome 10 and the protein tyrosine kinase ABL1 locus on chromosome 9 has been associated with acute lymphoblastic leukemia. [provided by RefSeq, Mar 2010]
Gene Name: Zinc Finger MIZ-type Containing 1
Chromosome: CHR10: 80828791 -81076285
Locus: 10q22.3
Gene Diseases
The ZMIZ1 ADK Fusion has been associated with the following diseases:
| Disease Name |
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| Uterine Carcinosarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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