ZFX-KLHL15 Fusion FISH Probe
The ZFX-KLHL15 Fusion FISH Probe is used to confirm a fusion of the ZFX and KLHL15 genes. The fusion of the ZFX and KLHL15 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ZFX-KLHL15-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| ZFX-KLHL15-20-RERE | 20 (40 μL) | 200 μL |
|
|
| ZFX-KLHL15-20-REOR | 20 (40 μL) | 200 μL |
|
|
| ZFX-KLHL15-20-REGO | 20 (40 μL) | 200 μL |
|
|
| ZFX-KLHL15-20-REGR | 20 (40 μL) | 200 μL |
|
|
| ZFX-KLHL15-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| ZFX-KLHL15-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| ZFX-KLHL15-20-OROR | 20 (40 μL) | 200 μL |
|
|
| ZFX-KLHL15-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| ZFX-KLHL15-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| ZFX-KLHL15-20-GORE | 20 (40 μL) | 200 μL |
|
|
| ZFX-KLHL15-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| ZFX-KLHL15-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| ZFX-KLHL15-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| ZFX-KLHL15-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| ZFX-KLHL15-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| ZFX-KLHL15-20-GROR | 20 (40 μL) | 200 μL |
|
|
| ZFX-KLHL15-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| ZFX-KLHL15-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| ZFX-KLHL15-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| ZFX-KLHL15-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| ZFX-KLHL15-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| ZFX-KLHL15-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| ZFX-KLHL15-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| ZFX-KLHL15-20-AQAQ | 20 (40 μL) | 200 μL |
|
ZFX Gene Summary
This gene on the X chromosome is structurally similar to a related gene on the Y chromosome. It encodes a member of the krueppel C2H2-type zinc-finger protein family. The full-length protein contains an acidic transcriptional activation domain (AD), a nuclear localization sequence (NLS) and a DNA binding domain (DBD) consisting of 13 C2H2-type zinc fingers. Studies in mouse embryonic and adult hematopoietic stem cells showed that this gene was required as a transcriptional regulator for self-renewal of both stem cell types, but it was dispensable for growth and differentiation of their progeny. Multiple alternatively spliced transcript variants encoding different isoforms have been identified, but the full-length nature of some variants has not been determined. [provided by RefSeq, May 2010]
Gene Name: Zinc Finger Protein, X-linked
Chromosome: CHRX: 24167761 -24234372
Locus: Xp22.11
KLHL15 Gene Summary
This gene encodes a member of the kelch-like family of proteins that share a common domain structure consisting of an N-terminal broad-complex, tramtrack, bric-a-brac/poxvirus and zinc finger domain and C-terminal kelch repeat motifs. The encoded protein may be involved in protein ubiquitination and cytoskeletal organization. [provided by RefSeq, Apr 2009]
Gene Name: Kelch Like Family Member 15
Chromosome: CHRX: 24001832 -24045303
Locus: Xp22.11
Gene Diseases
The ZFX KLHL15 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|