ZFR-TARS Fusion FISH Probe
The ZFR-TARS Fusion FISH Probe is used to confirm a fusion of the ZFR and TARS genes. The fusion of the ZFR and TARS genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ZFR-TARS-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ZFR-TARS-20-RERE | 20 (40 μL) | 200 μL |
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| ZFR-TARS-20-REOR | 20 (40 μL) | 200 μL |
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| ZFR-TARS-20-REGO | 20 (40 μL) | 200 μL |
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| ZFR-TARS-20-REGR | 20 (40 μL) | 200 μL |
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| ZFR-TARS-20-REAQ | 20 (40 μL) | 200 μL |
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| ZFR-TARS-20-ORRE | 20 (40 μL) | 200 μL |
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| ZFR-TARS-20-OROR | 20 (40 μL) | 200 μL |
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| ZFR-TARS-20-ORGO | 20 (40 μL) | 200 μL |
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| ZFR-TARS-20-ORAQ | 20 (40 μL) | 200 μL |
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| ZFR-TARS-20-GORE | 20 (40 μL) | 200 μL |
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| ZFR-TARS-20-GOOR | 20 (40 μL) | 200 μL |
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| ZFR-TARS-20-GOGO | 20 (40 μL) | 200 μL |
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| ZFR-TARS-20-GOGR | 20 (40 μL) | 200 μL |
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| ZFR-TARS-20-GOAQ | 20 (40 μL) | 200 μL |
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| ZFR-TARS-20-GRRE | 20 (40 μL) | 200 μL |
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| ZFR-TARS-20-GROR | 20 (40 μL) | 200 μL |
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| ZFR-TARS-20-GRGO | 20 (40 μL) | 200 μL |
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| ZFR-TARS-20-GRGR | 20 (40 μL) | 200 μL |
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| ZFR-TARS-20-GRAQ | 20 (40 μL) | 200 μL |
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| ZFR-TARS-20-AQRE | 20 (40 μL) | 200 μL |
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| ZFR-TARS-20-AQOR | 20 (40 μL) | 200 μL |
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| ZFR-TARS-20-AQGO | 20 (40 μL) | 200 μL |
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| ZFR-TARS-20-AQGR | 20 (40 μL) | 200 μL |
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| ZFR-TARS-20-AQAQ | 20 (40 μL) | 200 μL |
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TARS Gene Summary
Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Threonyl-tRNA synthetase belongs to the class-II aminoacyl-tRNA synthetase family [provided by RefSeq, Jul 2008]
Gene Name: Threonyl-tRNA Synthetase
Chromosome: CHR5: 33440897 -33468196
Locus: 5p13.3
ZFR Gene Summary
This gene encodes an RNA-binding protein characterized by its DZF (domain associated with zinc fingers) domain. The encoded protein may play a role in the nucleocytoplasmic shuttling of another RNA-binding protein, Staufen homolog 2, in neurons. Expression of this gene is regulated through alternative polyadenylation that mediates differential microRNA targeting. Elevated expression of this gene has been observed in human patients with pancreatic cancer and knockdown of this gene may result in reduced viability and invasion of pancreatic cancer cells. [provided by RefSeq, Sep 2016]
Gene Name: Zinc Finger RNA Binding Protein
Chromosome: CHR5: 32354455 -32444844
Locus: 5p13.3
Gene Diseases
The ZFR TARS Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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