ZFR-SND1 Fusion FISH Probe
The ZFR-SND1 Fusion FISH Probe is used to confirm a fusion of the ZFR and SND1 genes. The fusion of the ZFR and SND1 genes has been associated with Ovarian Serous Cystadenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ZFR-SND1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ZFR-SND1-20-RERE | 20 (40 μL) | 200 μL |
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| ZFR-SND1-20-REOR | 20 (40 μL) | 200 μL |
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| ZFR-SND1-20-REGO | 20 (40 μL) | 200 μL |
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| ZFR-SND1-20-REGR | 20 (40 μL) | 200 μL |
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| ZFR-SND1-20-REAQ | 20 (40 μL) | 200 μL |
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| ZFR-SND1-20-ORRE | 20 (40 μL) | 200 μL |
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| ZFR-SND1-20-OROR | 20 (40 μL) | 200 μL |
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| ZFR-SND1-20-ORGO | 20 (40 μL) | 200 μL |
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| ZFR-SND1-20-ORAQ | 20 (40 μL) | 200 μL |
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| ZFR-SND1-20-GORE | 20 (40 μL) | 200 μL |
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| ZFR-SND1-20-GOOR | 20 (40 μL) | 200 μL |
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| ZFR-SND1-20-GOGO | 20 (40 μL) | 200 μL |
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| ZFR-SND1-20-GOGR | 20 (40 μL) | 200 μL |
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| ZFR-SND1-20-GOAQ | 20 (40 μL) | 200 μL |
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| ZFR-SND1-20-GRRE | 20 (40 μL) | 200 μL |
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| ZFR-SND1-20-GROR | 20 (40 μL) | 200 μL |
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| ZFR-SND1-20-GRGO | 20 (40 μL) | 200 μL |
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| ZFR-SND1-20-GRGR | 20 (40 μL) | 200 μL |
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| ZFR-SND1-20-GRAQ | 20 (40 μL) | 200 μL |
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| ZFR-SND1-20-AQRE | 20 (40 μL) | 200 μL |
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| ZFR-SND1-20-AQOR | 20 (40 μL) | 200 μL |
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| ZFR-SND1-20-AQGO | 20 (40 μL) | 200 μL |
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| ZFR-SND1-20-AQGR | 20 (40 μL) | 200 μL |
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| ZFR-SND1-20-AQAQ | 20 (40 μL) | 200 μL |
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SND1 Gene Summary
This gene encodes a transcriptional co-activator that interacts with the acidic domain of Epstein-Barr virus nuclear antigen 2 (EBNA 2), a transcriptional activator that is required for B-lymphocyte transformation. Other transcription factors that interact with this protein are signal transducers and activators of transcription, STATs. This protein is also thought to be essential for normal cell growth. A similar protein in mammals and other organisms is a component of the RNA-induced silencing complex (RISC). [provided by RefSeq, Jul 2016]
Gene Name: Staphylococcal Nuclease And Tudor Domain Containing 1
Chromosome: CHR7: 127292201 -127732659
Locus: 7q32.1
ZFR Gene Summary
This gene encodes an RNA-binding protein characterized by its DZF (domain associated with zinc fingers) domain. The encoded protein may play a role in the nucleocytoplasmic shuttling of another RNA-binding protein, Staufen homolog 2, in neurons. Expression of this gene is regulated through alternative polyadenylation that mediates differential microRNA targeting. Elevated expression of this gene has been observed in human patients with pancreatic cancer and knockdown of this gene may result in reduced viability and invasion of pancreatic cancer cells. [provided by RefSeq, Sep 2016]
Gene Name: Zinc Finger RNA Binding Protein
Chromosome: CHR5: 32354455 -32444844
Locus: 5p13.3
Gene Diseases
The ZFR SND1 Fusion has been associated with the following diseases:
| Disease Name |
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| Ovarian Serous Cystadenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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