ZFR-PLEKHG4B Fusion FISH Probe
The ZFR-PLEKHG4B Fusion FISH Probe is used to confirm a fusion of the ZFR and PLEKHG4B genes. The fusion of the ZFR and PLEKHG4B genes has been associated with Head And Neck Squamous Cell Carcinoma . These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ZFR-PLEKHG4B-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ZFR-PLEKHG4B-20-RERE | 20 (40 μL) | 200 μL |
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| ZFR-PLEKHG4B-20-REOR | 20 (40 μL) | 200 μL |
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| ZFR-PLEKHG4B-20-REGO | 20 (40 μL) | 200 μL |
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| ZFR-PLEKHG4B-20-REGR | 20 (40 μL) | 200 μL |
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| ZFR-PLEKHG4B-20-REAQ | 20 (40 μL) | 200 μL |
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| ZFR-PLEKHG4B-20-ORRE | 20 (40 μL) | 200 μL |
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| ZFR-PLEKHG4B-20-OROR | 20 (40 μL) | 200 μL |
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| ZFR-PLEKHG4B-20-ORGO | 20 (40 μL) | 200 μL |
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| ZFR-PLEKHG4B-20-ORAQ | 20 (40 μL) | 200 μL |
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| ZFR-PLEKHG4B-20-GORE | 20 (40 μL) | 200 μL |
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| ZFR-PLEKHG4B-20-GOOR | 20 (40 μL) | 200 μL |
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| ZFR-PLEKHG4B-20-GOGO | 20 (40 μL) | 200 μL |
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| ZFR-PLEKHG4B-20-GOGR | 20 (40 μL) | 200 μL |
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| ZFR-PLEKHG4B-20-GOAQ | 20 (40 μL) | 200 μL |
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| ZFR-PLEKHG4B-20-GRRE | 20 (40 μL) | 200 μL |
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| ZFR-PLEKHG4B-20-GROR | 20 (40 μL) | 200 μL |
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| ZFR-PLEKHG4B-20-GRGO | 20 (40 μL) | 200 μL |
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| ZFR-PLEKHG4B-20-GRGR | 20 (40 μL) | 200 μL |
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| ZFR-PLEKHG4B-20-GRAQ | 20 (40 μL) | 200 μL |
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| ZFR-PLEKHG4B-20-AQRE | 20 (40 μL) | 200 μL |
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| ZFR-PLEKHG4B-20-AQOR | 20 (40 μL) | 200 μL |
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| ZFR-PLEKHG4B-20-AQGO | 20 (40 μL) | 200 μL |
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| ZFR-PLEKHG4B-20-AQGR | 20 (40 μL) | 200 μL |
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| ZFR-PLEKHG4B-20-AQAQ | 20 (40 μL) | 200 μL |
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ZFR Gene Summary
This gene encodes an RNA-binding protein characterized by its DZF (domain associated with zinc fingers) domain. The encoded protein may play a role in the nucleocytoplasmic shuttling of another RNA-binding protein, Staufen homolog 2, in neurons. Expression of this gene is regulated through alternative polyadenylation that mediates differential microRNA targeting. Elevated expression of this gene has been observed in human patients with pancreatic cancer and knockdown of this gene may result in reduced viability and invasion of pancreatic cancer cells. [provided by RefSeq, Sep 2016]
Gene Name: Zinc Finger RNA Binding Protein
Chromosome: CHR5: 32354455 -32444844
Locus: 5p13.3
PLEKHG4B Gene Summary
This gene encodes a large protein that contains a pleckstrin homology domain and may function as a guanine nucleotide exchange factor. [provided by RefSeq, May 2017]
Gene Name: Pleckstrin Homology And RhoGEF Domain Containing G4B
Chromosome: CHR5: 140372 -190087
Locus: 5p15.33
Gene Diseases
The ZFR PLEKHG4B Fusion has been associated with the following diseases:
| Disease Name |
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| Head And Neck Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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