ZFP91-RAB6A Fusion FISH Probe
The ZFP91-RAB6A Fusion FISH Probe is used to confirm a fusion of the ZFP91 and RAB6A genes. The fusion of the ZFP91 and RAB6A genes has been associated with Breast Invasive Carcinoma, Breast Invasive Carcinoma, Breast Invasive Carcinoma, Breast Invasive Carcinoma, and Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ZFP91-RAB6A-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ZFP91-RAB6A-20-RERE | 20 (40 μL) | 200 μL |
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| ZFP91-RAB6A-20-REOR | 20 (40 μL) | 200 μL |
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| ZFP91-RAB6A-20-REGO | 20 (40 μL) | 200 μL |
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| ZFP91-RAB6A-20-REGR | 20 (40 μL) | 200 μL |
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| ZFP91-RAB6A-20-REAQ | 20 (40 μL) | 200 μL |
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| ZFP91-RAB6A-20-ORRE | 20 (40 μL) | 200 μL |
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| ZFP91-RAB6A-20-OROR | 20 (40 μL) | 200 μL |
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| ZFP91-RAB6A-20-ORGO | 20 (40 μL) | 200 μL |
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| ZFP91-RAB6A-20-ORAQ | 20 (40 μL) | 200 μL |
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| ZFP91-RAB6A-20-GORE | 20 (40 μL) | 200 μL |
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| ZFP91-RAB6A-20-GOOR | 20 (40 μL) | 200 μL |
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| ZFP91-RAB6A-20-GOGO | 20 (40 μL) | 200 μL |
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| ZFP91-RAB6A-20-GOGR | 20 (40 μL) | 200 μL |
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| ZFP91-RAB6A-20-GOAQ | 20 (40 μL) | 200 μL |
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| ZFP91-RAB6A-20-GRRE | 20 (40 μL) | 200 μL |
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| ZFP91-RAB6A-20-GROR | 20 (40 μL) | 200 μL |
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| ZFP91-RAB6A-20-GRGO | 20 (40 μL) | 200 μL |
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| ZFP91-RAB6A-20-GRGR | 20 (40 μL) | 200 μL |
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| ZFP91-RAB6A-20-GRAQ | 20 (40 μL) | 200 μL |
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| ZFP91-RAB6A-20-AQRE | 20 (40 μL) | 200 μL |
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| ZFP91-RAB6A-20-AQOR | 20 (40 μL) | 200 μL |
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| ZFP91-RAB6A-20-AQGO | 20 (40 μL) | 200 μL |
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| ZFP91-RAB6A-20-AQGR | 20 (40 μL) | 200 μL |
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| ZFP91-RAB6A-20-AQAQ | 20 (40 μL) | 200 μL |
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RAB6A Gene Summary
This gene encodes a member of the RAB family, which belongs to the small GTPase superfamily. GTPases of the RAB family bind to various effectors to regulate the targeting and fusion of transport carriers to acceptor compartments. This protein is located at the Golgi apparatus, which regulates trafficking in both a retrograde (from early endosomes and Golgi to the endoplasmic reticulum) and an anterograde (from the Golgi to the plasma membrane) directions. Myosin II is an effector of this protein in these processes. This protein is also involved in assembly of human cytomegalovirus (HCMV) by interacting with the cellular protein Bicaudal D1, which interacts with the HCMV virion tegument protein, pp150. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011]
Gene Name: RAB6A, Member RAS Oncogene Family
Chromosome: CHR11: 73386682 -73472201
Locus: 11q13.4
ZFP91 Gene Summary
The protein encoded by this gene is a member of the zinc finger family of proteins. The gene product contains C2H2-type domains, which are the classical zinc finger domains found in numerous nucleic acid-binding proteins. This protein functions as a regulator of the non-canonical NF-kappaB pathway in lymphotoxin-beta receptor signaling. Alternative splicing results in multiple transcript variants. A read-through transcript variant composed of ZFP91 and the downstream CNTF gene sequence has been identified, but it is thought to be non-coding. Read-through transcription of ZFP91 and CNTF has also been observed in mouse. A ZFP91-related pseudogene has also been identified on chromosome 2. [provided by RefSeq, Oct 2010]
Gene Name: ZFP91 Zinc Finger Protein
Chromosome: CHR11: 58346586 -58389023
Locus: 11q12.1
Gene Diseases
The ZFP91 RAB6A Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
| Breast Invasive Carcinoma |
| Breast Invasive Carcinoma |
| Breast Invasive Carcinoma |
| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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