ZFP3-ARRB2 Fusion FISH Probe
The ZFP3-ARRB2 Fusion FISH Probe is used to confirm a fusion of the ZFP3 and ARRB2 genes. The fusion of the ZFP3 and ARRB2 genes has been associated with Uterine Carcinosarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ZFP3-ARRB2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ZFP3-ARRB2-20-RERE | 20 (40 μL) | 200 μL |
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| ZFP3-ARRB2-20-REOR | 20 (40 μL) | 200 μL |
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| ZFP3-ARRB2-20-REGO | 20 (40 μL) | 200 μL |
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| ZFP3-ARRB2-20-REGR | 20 (40 μL) | 200 μL |
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| ZFP3-ARRB2-20-REAQ | 20 (40 μL) | 200 μL |
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| ZFP3-ARRB2-20-ORRE | 20 (40 μL) | 200 μL |
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| ZFP3-ARRB2-20-OROR | 20 (40 μL) | 200 μL |
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| ZFP3-ARRB2-20-ORGO | 20 (40 μL) | 200 μL |
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| ZFP3-ARRB2-20-ORAQ | 20 (40 μL) | 200 μL |
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| ZFP3-ARRB2-20-GORE | 20 (40 μL) | 200 μL |
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| ZFP3-ARRB2-20-GOOR | 20 (40 μL) | 200 μL |
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| ZFP3-ARRB2-20-GOGO | 20 (40 μL) | 200 μL |
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| ZFP3-ARRB2-20-GOGR | 20 (40 μL) | 200 μL |
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| ZFP3-ARRB2-20-GOAQ | 20 (40 μL) | 200 μL |
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| ZFP3-ARRB2-20-GRRE | 20 (40 μL) | 200 μL |
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| ZFP3-ARRB2-20-GROR | 20 (40 μL) | 200 μL |
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| ZFP3-ARRB2-20-GRGO | 20 (40 μL) | 200 μL |
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| ZFP3-ARRB2-20-GRGR | 20 (40 μL) | 200 μL |
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| ZFP3-ARRB2-20-GRAQ | 20 (40 μL) | 200 μL |
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| ZFP3-ARRB2-20-AQRE | 20 (40 μL) | 200 μL |
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| ZFP3-ARRB2-20-AQOR | 20 (40 μL) | 200 μL |
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| ZFP3-ARRB2-20-AQGO | 20 (40 μL) | 200 μL |
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| ZFP3-ARRB2-20-AQGR | 20 (40 μL) | 200 μL |
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| ZFP3-ARRB2-20-AQAQ | 20 (40 μL) | 200 μL |
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ARRB2 Gene Summary
Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 2, like arrestin beta 1, was shown to inhibit beta-adrenergic receptor function in vitro. It is expressed at high levels in the central nervous system and may play a role in the regulation of synaptic receptors. Besides the brain, a cDNA for arrestin beta 2 was isolated from thyroid gland, and thus it may also be involved in hormone-specific desensitization of TSH receptors. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2012]
Gene Name: Arrestin Beta 2
Chromosome: CHR17: 4613788 -4624795
Locus: 17p13.2
ZFP3 Gene Summary
The ZFP3 Zinc Finger Protein (ZFP3) gene is located on chr17 :4981753-4999669 at 17p13.2.
Gene Name: ZFP3 Zinc Finger Protein
Chromosome: CHR17: 4981753 -4999669
Locus: 17p13.2
Gene Diseases
The ZFP3 ARRB2 Fusion has been associated with the following diseases:
| Disease Name |
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| Uterine Carcinosarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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