ZFHX4-VRK1 Fusion FISH Probe
The ZFHX4-VRK1 Fusion FISH Probe is used to confirm a fusion of the ZFHX4 and VRK1 genes. The fusion of the ZFHX4 and VRK1 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ZFHX4-VRK1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ZFHX4-VRK1-20-RERE | 20 (40 μL) | 200 μL |
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| ZFHX4-VRK1-20-REOR | 20 (40 μL) | 200 μL |
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| ZFHX4-VRK1-20-REGO | 20 (40 μL) | 200 μL |
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| ZFHX4-VRK1-20-REGR | 20 (40 μL) | 200 μL |
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| ZFHX4-VRK1-20-REAQ | 20 (40 μL) | 200 μL |
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| ZFHX4-VRK1-20-ORRE | 20 (40 μL) | 200 μL |
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| ZFHX4-VRK1-20-OROR | 20 (40 μL) | 200 μL |
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| ZFHX4-VRK1-20-ORGO | 20 (40 μL) | 200 μL |
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| ZFHX4-VRK1-20-ORAQ | 20 (40 μL) | 200 μL |
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| ZFHX4-VRK1-20-GORE | 20 (40 μL) | 200 μL |
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| ZFHX4-VRK1-20-GOOR | 20 (40 μL) | 200 μL |
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| ZFHX4-VRK1-20-GOGO | 20 (40 μL) | 200 μL |
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| ZFHX4-VRK1-20-GOGR | 20 (40 μL) | 200 μL |
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| ZFHX4-VRK1-20-GOAQ | 20 (40 μL) | 200 μL |
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| ZFHX4-VRK1-20-GRRE | 20 (40 μL) | 200 μL |
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| ZFHX4-VRK1-20-GROR | 20 (40 μL) | 200 μL |
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| ZFHX4-VRK1-20-GRGO | 20 (40 μL) | 200 μL |
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| ZFHX4-VRK1-20-GRGR | 20 (40 μL) | 200 μL |
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| ZFHX4-VRK1-20-GRAQ | 20 (40 μL) | 200 μL |
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| ZFHX4-VRK1-20-AQRE | 20 (40 μL) | 200 μL |
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| ZFHX4-VRK1-20-AQOR | 20 (40 μL) | 200 μL |
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| ZFHX4-VRK1-20-AQGO | 20 (40 μL) | 200 μL |
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| ZFHX4-VRK1-20-AQGR | 20 (40 μL) | 200 μL |
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| ZFHX4-VRK1-20-AQAQ | 20 (40 μL) | 200 μL |
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VRK1 Gene Summary
This gene encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. This gene is widely expressed in human tissues and has increased expression in actively dividing cells, such as those in testis, thymus, fetal liver, and carcinomas. Its protein localizes to the nucleus and has been shown to promote the stability and nuclear accumulation of a transcriptionally active p53 molecule and, in vitro, to phosphorylate Thr18 of p53 and reduce p53 ubiquitination. This gene, therefore, may regulate cell proliferation. This protein also phosphorylates histone, casein, and the transcription factors ATF2 (activating transcription factor 2) and c-JUN. [provided by RefSeq, Jul 2008]
Gene Name: Vaccinia Related Kinase 1
Chromosome: CHR14: 97263683 -97347951
Locus: 14q32.2
ZFHX4 Gene Summary
The Zinc Finger Homeobox 4 (ZFHX4) gene is located on chr8 :77593514-77779521 at 8q21.13.
Gene Name: Zinc Finger Homeobox 4
Chromosome: CHR8: 77593514 -77779521
Locus: 8q21.13
Gene Diseases
The ZFHX4 VRK1 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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