ZFHX3-ZNF821 Fusion FISH Probe
The ZFHX3-ZNF821 Fusion FISH Probe is used to confirm a fusion of the ZFHX3 and ZNF821 genes. The fusion of the ZFHX3 and ZNF821 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ZFHX3-ZNF821-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ZFHX3-ZNF821-20-RERE | 20 (40 μL) | 200 μL |
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| ZFHX3-ZNF821-20-REOR | 20 (40 μL) | 200 μL |
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| ZFHX3-ZNF821-20-REGO | 20 (40 μL) | 200 μL |
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| ZFHX3-ZNF821-20-REGR | 20 (40 μL) | 200 μL |
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| ZFHX3-ZNF821-20-REAQ | 20 (40 μL) | 200 μL |
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| ZFHX3-ZNF821-20-ORRE | 20 (40 μL) | 200 μL |
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| ZFHX3-ZNF821-20-OROR | 20 (40 μL) | 200 μL |
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| ZFHX3-ZNF821-20-ORGO | 20 (40 μL) | 200 μL |
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| ZFHX3-ZNF821-20-ORAQ | 20 (40 μL) | 200 μL |
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| ZFHX3-ZNF821-20-GORE | 20 (40 μL) | 200 μL |
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| ZFHX3-ZNF821-20-GOOR | 20 (40 μL) | 200 μL |
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| ZFHX3-ZNF821-20-GOGO | 20 (40 μL) | 200 μL |
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| ZFHX3-ZNF821-20-GOGR | 20 (40 μL) | 200 μL |
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| ZFHX3-ZNF821-20-GOAQ | 20 (40 μL) | 200 μL |
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| ZFHX3-ZNF821-20-GRRE | 20 (40 μL) | 200 μL |
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| ZFHX3-ZNF821-20-GROR | 20 (40 μL) | 200 μL |
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| ZFHX3-ZNF821-20-GRGO | 20 (40 μL) | 200 μL |
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| ZFHX3-ZNF821-20-GRGR | 20 (40 μL) | 200 μL |
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| ZFHX3-ZNF821-20-GRAQ | 20 (40 μL) | 200 μL |
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| ZFHX3-ZNF821-20-AQRE | 20 (40 μL) | 200 μL |
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| ZFHX3-ZNF821-20-AQOR | 20 (40 μL) | 200 μL |
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| ZFHX3-ZNF821-20-AQGO | 20 (40 μL) | 200 μL |
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| ZFHX3-ZNF821-20-AQGR | 20 (40 μL) | 200 μL |
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| ZFHX3-ZNF821-20-AQAQ | 20 (40 μL) | 200 μL |
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ZFHX3 Gene Summary
This gene encodes a transcription factor with multiple homeodomains and zinc finger motifs, and regulates myogenic and neuronal differentiation. The encoded protein suppresses expression of the alpha-fetoprotein gene by binding to an AT-rich enhancer motif. The protein has also been shown to negatively regulate c-Myb, and transactivate the cell cycle inhibitor cyclin-dependent kinase inhibitor 1A (also known as p21CIP1). This gene is reported to function as a tumor suppressor in several cancers, and sequence variants of this gene are also associated with atrial fibrillation. Multiple transcript variants expressed from alternate promoters and encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]
Gene Name: Zinc Finger Homeobox 3
Chromosome: CHR16: 72816785 -73092534
Locus: 16q22.2-q22.3
ZNF821 Gene Summary
This gene encodes a protein with two C2H2 zinc finger motifs and a score-and-three (23)-amino acid peptide repeat (STPR) domain. The STPR domain of the encoded protein binds to double stranded DNA and may also contain a nuclear localization signal, suggesting that this protein interacts with chromosomal DNA. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]
Gene Name: Zinc Finger Protein 821
Chromosome: CHR16: 71893582 -71918093
Locus: 16q22.2
Gene Diseases
The ZFHX3 ZNF821 Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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