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ZFAND3-RNF8 Fusion FISH Probe

The ZFAND3-RNF8 Fusion FISH Probe is used to confirm a fusion of the ZFAND3 and RNF8 genes. The fusion of the ZFAND3 and RNF8 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
ZFAND3-RNF8-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
ZFAND3-RNF8-20-RERE 20 (40 μL) 200 μL
ZFAND3-RNF8-20-REOR 20 (40 μL) 200 μL
ZFAND3-RNF8-20-REGO 20 (40 μL) 200 μL
ZFAND3-RNF8-20-REGR 20 (40 μL) 200 μL
ZFAND3-RNF8-20-REAQ 20 (40 μL) 200 μL
ZFAND3-RNF8-20-ORRE 20 (40 μL) 200 μL
ZFAND3-RNF8-20-OROR 20 (40 μL) 200 μL
ZFAND3-RNF8-20-ORGO 20 (40 μL) 200 μL
ZFAND3-RNF8-20-ORAQ 20 (40 μL) 200 μL
ZFAND3-RNF8-20-GORE 20 (40 μL) 200 μL
ZFAND3-RNF8-20-GOOR 20 (40 μL) 200 μL
ZFAND3-RNF8-20-GOGO 20 (40 μL) 200 μL
ZFAND3-RNF8-20-GOGR 20 (40 μL) 200 μL
ZFAND3-RNF8-20-GOAQ 20 (40 μL) 200 μL
ZFAND3-RNF8-20-GRRE 20 (40 μL) 200 μL
ZFAND3-RNF8-20-GROR 20 (40 μL) 200 μL
ZFAND3-RNF8-20-GRGO 20 (40 μL) 200 μL
ZFAND3-RNF8-20-GRGR 20 (40 μL) 200 μL
ZFAND3-RNF8-20-GRAQ 20 (40 μL) 200 μL
ZFAND3-RNF8-20-AQRE 20 (40 μL) 200 μL
ZFAND3-RNF8-20-AQOR 20 (40 μL) 200 μL
ZFAND3-RNF8-20-AQGO 20 (40 μL) 200 μL
ZFAND3-RNF8-20-AQGR 20 (40 μL) 200 μL
ZFAND3-RNF8-20-AQAQ 20 (40 μL) 200 μL

RNF8 Gene Summary

The protein encoded by this gene contains a RING finger motif and an FHA domain. This protein has been shown to interact with several class II ubiquitin-conjugating enzymes (E2), including UBE2E1/UBCH6, UBE2E2, and UBE2E3, and may act as an ubiquitin ligase (E3) in the ubiquitination of certain nuclear proteins. This protein is also known to play a role in the DNA damage response and depletion of this protein causes cell growth inhibition and cell cycle arrest. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2012]

Gene Name: Ring Finger Protein 8

Chromosome: CHR6: 37321747 -37362514

Locus: 6p21.2

ZFAND3 Gene Summary

The Zinc Finger AN1-type Containing 3 (ZFAND3) gene is located on chr6 :37787306-38122399 at 6p21.2.

Gene Name: Zinc Finger AN1-type Containing 3

Chromosome: CHR6: 37787306 -38122399

Locus: 6p21.2

Gene Diseases

The ZFAND3 RNF8 Fusion has been associated with the following diseases:

Disease Name
Breast Invasive Carcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.