ZFAND3-RNF8 Fusion FISH Probe
The ZFAND3-RNF8 Fusion FISH Probe is used to confirm a fusion of the ZFAND3 and RNF8 genes. The fusion of the ZFAND3 and RNF8 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ZFAND3-RNF8-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ZFAND3-RNF8-20-RERE | 20 (40 μL) | 200 μL |
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| ZFAND3-RNF8-20-REOR | 20 (40 μL) | 200 μL |
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| ZFAND3-RNF8-20-REGO | 20 (40 μL) | 200 μL |
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| ZFAND3-RNF8-20-REGR | 20 (40 μL) | 200 μL |
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| ZFAND3-RNF8-20-REAQ | 20 (40 μL) | 200 μL |
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| ZFAND3-RNF8-20-ORRE | 20 (40 μL) | 200 μL |
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| ZFAND3-RNF8-20-OROR | 20 (40 μL) | 200 μL |
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| ZFAND3-RNF8-20-ORGO | 20 (40 μL) | 200 μL |
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| ZFAND3-RNF8-20-ORAQ | 20 (40 μL) | 200 μL |
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| ZFAND3-RNF8-20-GORE | 20 (40 μL) | 200 μL |
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| ZFAND3-RNF8-20-GOOR | 20 (40 μL) | 200 μL |
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| ZFAND3-RNF8-20-GOGO | 20 (40 μL) | 200 μL |
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| ZFAND3-RNF8-20-GOGR | 20 (40 μL) | 200 μL |
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| ZFAND3-RNF8-20-GOAQ | 20 (40 μL) | 200 μL |
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| ZFAND3-RNF8-20-GRRE | 20 (40 μL) | 200 μL |
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| ZFAND3-RNF8-20-GROR | 20 (40 μL) | 200 μL |
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| ZFAND3-RNF8-20-GRGO | 20 (40 μL) | 200 μL |
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| ZFAND3-RNF8-20-GRGR | 20 (40 μL) | 200 μL |
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| ZFAND3-RNF8-20-GRAQ | 20 (40 μL) | 200 μL |
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| ZFAND3-RNF8-20-AQRE | 20 (40 μL) | 200 μL |
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| ZFAND3-RNF8-20-AQOR | 20 (40 μL) | 200 μL |
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| ZFAND3-RNF8-20-AQGO | 20 (40 μL) | 200 μL |
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| ZFAND3-RNF8-20-AQGR | 20 (40 μL) | 200 μL |
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| ZFAND3-RNF8-20-AQAQ | 20 (40 μL) | 200 μL |
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RNF8 Gene Summary
The protein encoded by this gene contains a RING finger motif and an FHA domain. This protein has been shown to interact with several class II ubiquitin-conjugating enzymes (E2), including UBE2E1/UBCH6, UBE2E2, and UBE2E3, and may act as an ubiquitin ligase (E3) in the ubiquitination of certain nuclear proteins. This protein is also known to play a role in the DNA damage response and depletion of this protein causes cell growth inhibition and cell cycle arrest. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2012]
Gene Name: Ring Finger Protein 8
Chromosome: CHR6: 37321747 -37362514
Locus: 6p21.2
ZFAND3 Gene Summary
The Zinc Finger AN1-type Containing 3 (ZFAND3) gene is located on chr6 :37787306-38122399 at 6p21.2.
Gene Name: Zinc Finger AN1-type Containing 3
Chromosome: CHR6: 37787306 -38122399
Locus: 6p21.2
Gene Diseases
The ZFAND3 RNF8 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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