ZDHHC20-GJB6 Fusion FISH Probe
The ZDHHC20-GJB6 Fusion FISH Probe is used to confirm a fusion of the ZDHHC20 and GJB6 genes. The fusion of the ZDHHC20 and GJB6 genes has been associated with Pancreatic Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ZDHHC20-GJB6-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ZDHHC20-GJB6-20-RERE | 20 (40 μL) | 200 μL |
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| ZDHHC20-GJB6-20-REOR | 20 (40 μL) | 200 μL |
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| ZDHHC20-GJB6-20-REGO | 20 (40 μL) | 200 μL |
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| ZDHHC20-GJB6-20-REGR | 20 (40 μL) | 200 μL |
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| ZDHHC20-GJB6-20-REAQ | 20 (40 μL) | 200 μL |
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| ZDHHC20-GJB6-20-ORRE | 20 (40 μL) | 200 μL |
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| ZDHHC20-GJB6-20-OROR | 20 (40 μL) | 200 μL |
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| ZDHHC20-GJB6-20-ORGO | 20 (40 μL) | 200 μL |
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| ZDHHC20-GJB6-20-ORAQ | 20 (40 μL) | 200 μL |
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| ZDHHC20-GJB6-20-GORE | 20 (40 μL) | 200 μL |
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| ZDHHC20-GJB6-20-GOOR | 20 (40 μL) | 200 μL |
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| ZDHHC20-GJB6-20-GOGO | 20 (40 μL) | 200 μL |
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| ZDHHC20-GJB6-20-GOGR | 20 (40 μL) | 200 μL |
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| ZDHHC20-GJB6-20-GOAQ | 20 (40 μL) | 200 μL |
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| ZDHHC20-GJB6-20-GRRE | 20 (40 μL) | 200 μL |
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| ZDHHC20-GJB6-20-GROR | 20 (40 μL) | 200 μL |
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| ZDHHC20-GJB6-20-GRGO | 20 (40 μL) | 200 μL |
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| ZDHHC20-GJB6-20-GRGR | 20 (40 μL) | 200 μL |
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| ZDHHC20-GJB6-20-GRAQ | 20 (40 μL) | 200 μL |
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| ZDHHC20-GJB6-20-AQRE | 20 (40 μL) | 200 μL |
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| ZDHHC20-GJB6-20-AQOR | 20 (40 μL) | 200 μL |
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| ZDHHC20-GJB6-20-AQGO | 20 (40 μL) | 200 μL |
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| ZDHHC20-GJB6-20-AQGR | 20 (40 μL) | 200 μL |
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| ZDHHC20-GJB6-20-AQAQ | 20 (40 μL) | 200 μL |
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GJB6 Gene Summary
Gap junctions allow the transport of ions and metabolites between the cytoplasm of adjacent cells. They are formed by two hemichannels, made up of six connexin proteins assembled in groups. Each connexin protein has four transmembrane segments, two extracellular loops, a cytoplasmic loop formed between the two inner transmembrane segments, and the N- and C-terminus both being in the cytoplasm. The specificity of the gap junction is determined by which connexin proteins comprise the hemichannel. In the past, connexin protein names were based on their molecular weight, however the new nomenclature uses sequential numbers based on which form (alpha or beta) of the gap junction is present. This gene encodes one of the connexin proteins. Mutations in this gene have been found in some forms of deafness and in some families with hidrotic ectodermal dysplasia. [provided by RefSeq, Jul 2008]
Gene Name: Gap Junction Protein Beta 6
Chromosome: CHR13: 20796100 -20806534
Locus: 13q12.11
ZDHHC20 Gene Summary
The Zinc Finger DHHC-type Containing 20 (ZDHHC20) gene is located on chr13 :21946709-22033508 at 13q12.11.
Gene Name: Zinc Finger DHHC-type Containing 20
Chromosome: CHR13: 21946709 -22033508
Locus: 13q12.11
Gene Diseases
The ZDHHC20 GJB6 Fusion has been associated with the following diseases:
| Disease Name |
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| Pancreatic Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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