ZC3H3-SCRIB Fusion FISH Probe
The ZC3H3-SCRIB Fusion FISH Probe is used to confirm a fusion of the ZC3H3 and SCRIB genes. The fusion of the ZC3H3 and SCRIB genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ZC3H3-SCRIB-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ZC3H3-SCRIB-20-RERE | 20 (40 μL) | 200 μL |
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| ZC3H3-SCRIB-20-REOR | 20 (40 μL) | 200 μL |
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| ZC3H3-SCRIB-20-REGO | 20 (40 μL) | 200 μL |
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| ZC3H3-SCRIB-20-REGR | 20 (40 μL) | 200 μL |
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| ZC3H3-SCRIB-20-REAQ | 20 (40 μL) | 200 μL |
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| ZC3H3-SCRIB-20-ORRE | 20 (40 μL) | 200 μL |
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| ZC3H3-SCRIB-20-OROR | 20 (40 μL) | 200 μL |
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| ZC3H3-SCRIB-20-ORGO | 20 (40 μL) | 200 μL |
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| ZC3H3-SCRIB-20-ORAQ | 20 (40 μL) | 200 μL |
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| ZC3H3-SCRIB-20-GORE | 20 (40 μL) | 200 μL |
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| ZC3H3-SCRIB-20-GOOR | 20 (40 μL) | 200 μL |
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| ZC3H3-SCRIB-20-GOGO | 20 (40 μL) | 200 μL |
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| ZC3H3-SCRIB-20-GOGR | 20 (40 μL) | 200 μL |
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| ZC3H3-SCRIB-20-GOAQ | 20 (40 μL) | 200 μL |
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| ZC3H3-SCRIB-20-GRRE | 20 (40 μL) | 200 μL |
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| ZC3H3-SCRIB-20-GROR | 20 (40 μL) | 200 μL |
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| ZC3H3-SCRIB-20-GRGO | 20 (40 μL) | 200 μL |
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| ZC3H3-SCRIB-20-GRGR | 20 (40 μL) | 200 μL |
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| ZC3H3-SCRIB-20-GRAQ | 20 (40 μL) | 200 μL |
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| ZC3H3-SCRIB-20-AQRE | 20 (40 μL) | 200 μL |
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| ZC3H3-SCRIB-20-AQOR | 20 (40 μL) | 200 μL |
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| ZC3H3-SCRIB-20-AQGO | 20 (40 μL) | 200 μL |
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| ZC3H3-SCRIB-20-AQGR | 20 (40 μL) | 200 μL |
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| ZC3H3-SCRIB-20-AQAQ | 20 (40 μL) | 200 μL |
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ZC3H3 Gene Summary
The Zinc Finger CCCH-type Containing 3 (ZC3H3) gene is located on chr8 :144519824-144623620 at 8q24.3.
Gene Name: Zinc Finger CCCH-type Containing 3
Chromosome: CHR8: 144519824 -144623620
Locus: 8q24.3
SCRIB Gene Summary
This gene encodes a protein that was identified as being similar to the Drosophila scribble protein. The mammalian protein is involved in tumor suppression pathways. As a scaffold protein involved in cell polarization processes, this protein binds to many other proteins. The encoded protein binds to papillomavirus E6 protein via its PDZ domain and the C-terminus of E6. Two alternatively spliced transcript variants that encode different protein isoforms have been found for this gene. [provided by RefSeq, Nov 2011]
Gene Name: Scribbled Planar Cell Polarity Protein
Chromosome: CHR8: 144873089 -144897549
Locus: 8q24.3
Gene Diseases
The ZC3H3 SCRIB Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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