ZBTB7B-NUCKS1 Fusion FISH Probe
The ZBTB7B-NUCKS1 Fusion FISH Probe is used to confirm a fusion of the ZBTB7B and NUCKS1 genes. The fusion of the ZBTB7B and NUCKS1 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ZBTB7B-NUCKS1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| ZBTB7B-NUCKS1-20-RERE | 20 (40 μL) | 200 μL |
|
|
| ZBTB7B-NUCKS1-20-REOR | 20 (40 μL) | 200 μL |
|
|
| ZBTB7B-NUCKS1-20-REGO | 20 (40 μL) | 200 μL |
|
|
| ZBTB7B-NUCKS1-20-REGR | 20 (40 μL) | 200 μL |
|
|
| ZBTB7B-NUCKS1-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| ZBTB7B-NUCKS1-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| ZBTB7B-NUCKS1-20-OROR | 20 (40 μL) | 200 μL |
|
|
| ZBTB7B-NUCKS1-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| ZBTB7B-NUCKS1-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| ZBTB7B-NUCKS1-20-GORE | 20 (40 μL) | 200 μL |
|
|
| ZBTB7B-NUCKS1-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| ZBTB7B-NUCKS1-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| ZBTB7B-NUCKS1-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| ZBTB7B-NUCKS1-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| ZBTB7B-NUCKS1-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| ZBTB7B-NUCKS1-20-GROR | 20 (40 μL) | 200 μL |
|
|
| ZBTB7B-NUCKS1-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| ZBTB7B-NUCKS1-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| ZBTB7B-NUCKS1-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| ZBTB7B-NUCKS1-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| ZBTB7B-NUCKS1-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| ZBTB7B-NUCKS1-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| ZBTB7B-NUCKS1-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| ZBTB7B-NUCKS1-20-AQAQ | 20 (40 μL) | 200 μL |
|
ZBTB7B Gene Summary
This gene encodes a zinc finger-containing transcription factor that acts as a key regulator of lineage commitment of immature T-cell precursors. It is necessary and sufficient for commitment of CD4 lineage, while its absence causes CD8 commitment. It also functions as a transcriptional repressor of type I collagen genes. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012]
Gene Name: Zinc Finger And BTB Domain Containing 7B
Chromosome: CHR1: 154975111 -154990999
Locus: 1q21.3
NUCKS1 Gene Summary
This gene encodes a nuclear protein that is highly conserved in vertebrates. The conserved regions of the protein contain several consensus phosphorylation sites for casein kinase II and cyclin-dependent kinases, two putative nuclear localization signals, and a basic DNA-binding domain. It is phosphorylated in vivo by Cdk1 during mitosis of the cell cycle. [provided by RefSeq, Aug 2010]
Gene Name: Nuclear Casein Kinase And Cyclin Dependent Kinase Substrate 1
Chromosome: CHR1: 205681946 -205719372
Locus: 1q32.1
Gene Diseases
The ZBTB7B NUCKS1 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|