ZBTB20-PTPRD Fusion FISH Probe
The ZBTB20-PTPRD Fusion FISH Probe is used to confirm a fusion of the ZBTB20 and PTPRD genes. The fusion of the ZBTB20 and PTPRD genes has been associated with Liver Hepatocellular Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ZBTB20-PTPRD-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| ZBTB20-PTPRD-20-RERE | 20 (40 μL) | 200 μL |
|
|
| ZBTB20-PTPRD-20-REOR | 20 (40 μL) | 200 μL |
|
|
| ZBTB20-PTPRD-20-REGO | 20 (40 μL) | 200 μL |
|
|
| ZBTB20-PTPRD-20-REGR | 20 (40 μL) | 200 μL |
|
|
| ZBTB20-PTPRD-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| ZBTB20-PTPRD-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| ZBTB20-PTPRD-20-OROR | 20 (40 μL) | 200 μL |
|
|
| ZBTB20-PTPRD-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| ZBTB20-PTPRD-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| ZBTB20-PTPRD-20-GORE | 20 (40 μL) | 200 μL |
|
|
| ZBTB20-PTPRD-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| ZBTB20-PTPRD-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| ZBTB20-PTPRD-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| ZBTB20-PTPRD-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| ZBTB20-PTPRD-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| ZBTB20-PTPRD-20-GROR | 20 (40 μL) | 200 μL |
|
|
| ZBTB20-PTPRD-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| ZBTB20-PTPRD-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| ZBTB20-PTPRD-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| ZBTB20-PTPRD-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| ZBTB20-PTPRD-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| ZBTB20-PTPRD-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| ZBTB20-PTPRD-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| ZBTB20-PTPRD-20-AQAQ | 20 (40 μL) | 200 μL |
|
PTPRD Gene Summary
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular region, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this protein is composed of three Ig-like and eight fibronectin type III-like domains. Studies of the similar genes in chicken and fly suggest the role of this PTP is in promoting neurite growth, and regulating neurons axon guidance. Multiple alternatively spliced transcript variants of this gene have been reported. A related pseudogene has been identified on chromosome 5. [provided by RefSeq, Jan 2010]
Gene Name: Protein Tyrosine Phosphatase, Receptor Type D
Chromosome: CHR9: 8314245 -10612723
Locus: 9p24.1-p23
ZBTB20 Gene Summary
This gene, which was initially designated as dendritic cell-derived BTB/POZ zinc finger (DPZF), belongs to a family of transcription factors with an N-terminal BTB/POZ domain and a C-terminal DNA-bindng zinc finger domain. The BTB/POZ domain is a hydrophobic region of approximately 120 aa which mediates association with other BTB/POZ domain-containing proteins. This gene acts as a transcriptional repressor and plays a role in many processes including neurogenesis, glucose homeostasis, and postnatal growth. Mutations in this gene have been associated with Primrose syndrome as well as the 3q13.31 microdeletion syndrome. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Feb 2017]
Gene Name: Zinc Finger And BTB Domain Containing 20
Chromosome: CHR3: 114056946 -114866127
Locus: 3q13.31
Gene Diseases
The ZBTB20 PTPRD Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Liver Hepatocellular Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|