ZBTB20-PGD Fusion FISH Probe
The ZBTB20-PGD Fusion FISH Probe is used to confirm a fusion of the ZBTB20 and PGD genes. The fusion of the ZBTB20 and PGD genes has been associated with Cervical Squamous Cell Carcinoma And Endocervical Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ZBTB20-PGD-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ZBTB20-PGD-20-RERE | 20 (40 μL) | 200 μL |
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| ZBTB20-PGD-20-REOR | 20 (40 μL) | 200 μL |
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| ZBTB20-PGD-20-REGO | 20 (40 μL) | 200 μL |
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| ZBTB20-PGD-20-REGR | 20 (40 μL) | 200 μL |
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| ZBTB20-PGD-20-REAQ | 20 (40 μL) | 200 μL |
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| ZBTB20-PGD-20-ORRE | 20 (40 μL) | 200 μL |
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| ZBTB20-PGD-20-OROR | 20 (40 μL) | 200 μL |
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| ZBTB20-PGD-20-ORGO | 20 (40 μL) | 200 μL |
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| ZBTB20-PGD-20-ORAQ | 20 (40 μL) | 200 μL |
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| ZBTB20-PGD-20-GORE | 20 (40 μL) | 200 μL |
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| ZBTB20-PGD-20-GOOR | 20 (40 μL) | 200 μL |
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| ZBTB20-PGD-20-GOGO | 20 (40 μL) | 200 μL |
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| ZBTB20-PGD-20-GOGR | 20 (40 μL) | 200 μL |
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| ZBTB20-PGD-20-GOAQ | 20 (40 μL) | 200 μL |
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| ZBTB20-PGD-20-GRRE | 20 (40 μL) | 200 μL |
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| ZBTB20-PGD-20-GROR | 20 (40 μL) | 200 μL |
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| ZBTB20-PGD-20-GRGO | 20 (40 μL) | 200 μL |
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| ZBTB20-PGD-20-GRGR | 20 (40 μL) | 200 μL |
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| ZBTB20-PGD-20-GRAQ | 20 (40 μL) | 200 μL |
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| ZBTB20-PGD-20-AQRE | 20 (40 μL) | 200 μL |
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| ZBTB20-PGD-20-AQOR | 20 (40 μL) | 200 μL |
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| ZBTB20-PGD-20-AQGO | 20 (40 μL) | 200 μL |
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| ZBTB20-PGD-20-AQGR | 20 (40 μL) | 200 μL |
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| ZBTB20-PGD-20-AQAQ | 20 (40 μL) | 200 μL |
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PGD Gene Summary
6-phosphogluconate dehydrogenase is the second dehydrogenase in the pentose phosphate shunt. Deficiency of this enzyme is generally asymptomatic, and the inheritance of this disorder is autosomal dominant. Hemolysis results from combined deficiency of 6-phosphogluconate dehydrogenase and 6-phosphogluconolactonase suggesting a synergism of the two enzymopathies. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2015]
Gene Name: Phosphogluconate Dehydrogenase
Chromosome: CHR1: 10459084 -10480201
Locus: 1p36.22
ZBTB20 Gene Summary
This gene, which was initially designated as dendritic cell-derived BTB/POZ zinc finger (DPZF), belongs to a family of transcription factors with an N-terminal BTB/POZ domain and a C-terminal DNA-bindng zinc finger domain. The BTB/POZ domain is a hydrophobic region of approximately 120 aa which mediates association with other BTB/POZ domain-containing proteins. This gene acts as a transcriptional repressor and plays a role in many processes including neurogenesis, glucose homeostasis, and postnatal growth. Mutations in this gene have been associated with Primrose syndrome as well as the 3q13.31 microdeletion syndrome. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Feb 2017]
Gene Name: Zinc Finger And BTB Domain Containing 20
Chromosome: CHR3: 114056946 -114866127
Locus: 3q13.31
Gene Diseases
The ZBTB20 PGD Fusion has been associated with the following diseases:
| Disease Name |
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| Cervical Squamous Cell Carcinoma And Endocervical Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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