ZBTB20-DPYSL2 Fusion FISH Probe
The ZBTB20-DPYSL2 Fusion FISH Probe is used to confirm a fusion of the ZBTB20 and DPYSL2 genes. The fusion of the ZBTB20 and DPYSL2 genes has been associated with Colon Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ZBTB20-DPYSL2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ZBTB20-DPYSL2-20-RERE | 20 (40 μL) | 200 μL |
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| ZBTB20-DPYSL2-20-REOR | 20 (40 μL) | 200 μL |
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| ZBTB20-DPYSL2-20-REGO | 20 (40 μL) | 200 μL |
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| ZBTB20-DPYSL2-20-REGR | 20 (40 μL) | 200 μL |
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| ZBTB20-DPYSL2-20-REAQ | 20 (40 μL) | 200 μL |
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| ZBTB20-DPYSL2-20-ORRE | 20 (40 μL) | 200 μL |
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| ZBTB20-DPYSL2-20-OROR | 20 (40 μL) | 200 μL |
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| ZBTB20-DPYSL2-20-ORGO | 20 (40 μL) | 200 μL |
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| ZBTB20-DPYSL2-20-ORAQ | 20 (40 μL) | 200 μL |
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| ZBTB20-DPYSL2-20-GORE | 20 (40 μL) | 200 μL |
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| ZBTB20-DPYSL2-20-GOOR | 20 (40 μL) | 200 μL |
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| ZBTB20-DPYSL2-20-GOGO | 20 (40 μL) | 200 μL |
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| ZBTB20-DPYSL2-20-GOGR | 20 (40 μL) | 200 μL |
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| ZBTB20-DPYSL2-20-GOAQ | 20 (40 μL) | 200 μL |
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| ZBTB20-DPYSL2-20-GRRE | 20 (40 μL) | 200 μL |
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| ZBTB20-DPYSL2-20-GROR | 20 (40 μL) | 200 μL |
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| ZBTB20-DPYSL2-20-GRGO | 20 (40 μL) | 200 μL |
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| ZBTB20-DPYSL2-20-GRGR | 20 (40 μL) | 200 μL |
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| ZBTB20-DPYSL2-20-GRAQ | 20 (40 μL) | 200 μL |
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| ZBTB20-DPYSL2-20-AQRE | 20 (40 μL) | 200 μL |
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| ZBTB20-DPYSL2-20-AQOR | 20 (40 μL) | 200 μL |
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| ZBTB20-DPYSL2-20-AQGO | 20 (40 μL) | 200 μL |
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| ZBTB20-DPYSL2-20-AQGR | 20 (40 μL) | 200 μL |
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| ZBTB20-DPYSL2-20-AQAQ | 20 (40 μL) | 200 μL |
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DPYSL2 Gene Summary
This gene encodes a member of the collapsin response mediator protein family. Collapsin response mediator proteins form homo- and hetero-tetramers and facilitate neuron guidance, growth and polarity. The encoded protein promotes microtubule assembly and is required for Sema3A-mediated growth cone collapse, and also plays a role in synaptic signaling through interactions with calcium channels. This gene has been implicated in multiple neurological disorders, and hyperphosphorylation of the encoded protein may play a key role in the development of Alzheimer's disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011]
Gene Name: Dihydropyrimidinase Like 2
Chromosome: CHR8: 26371708 -26515693
Locus: 8p21.2
ZBTB20 Gene Summary
This gene, which was initially designated as dendritic cell-derived BTB/POZ zinc finger (DPZF), belongs to a family of transcription factors with an N-terminal BTB/POZ domain and a C-terminal DNA-bindng zinc finger domain. The BTB/POZ domain is a hydrophobic region of approximately 120 aa which mediates association with other BTB/POZ domain-containing proteins. This gene acts as a transcriptional repressor and plays a role in many processes including neurogenesis, glucose homeostasis, and postnatal growth. Mutations in this gene have been associated with Primrose syndrome as well as the 3q13.31 microdeletion syndrome. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Feb 2017]
Gene Name: Zinc Finger And BTB Domain Containing 20
Chromosome: CHR3: 114056946 -114866127
Locus: 3q13.31
Gene Diseases
The ZBTB20 DPYSL2 Fusion has been associated with the following diseases:
| Disease Name |
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| Colon Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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