ZBTB20-CD200R1 Fusion FISH Probe
The ZBTB20-CD200R1 Fusion FISH Probe is used to confirm a fusion of the ZBTB20 and CD200R1 genes. The fusion of the ZBTB20 and CD200R1 genes has been associated with Kidney Renal Clear Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ZBTB20-CD200R1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ZBTB20-CD200R1-20-RERE | 20 (40 μL) | 200 μL |
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| ZBTB20-CD200R1-20-REOR | 20 (40 μL) | 200 μL |
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| ZBTB20-CD200R1-20-REGO | 20 (40 μL) | 200 μL |
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| ZBTB20-CD200R1-20-REGR | 20 (40 μL) | 200 μL |
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| ZBTB20-CD200R1-20-REAQ | 20 (40 μL) | 200 μL |
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| ZBTB20-CD200R1-20-ORRE | 20 (40 μL) | 200 μL |
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| ZBTB20-CD200R1-20-OROR | 20 (40 μL) | 200 μL |
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| ZBTB20-CD200R1-20-ORGO | 20 (40 μL) | 200 μL |
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| ZBTB20-CD200R1-20-ORAQ | 20 (40 μL) | 200 μL |
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| ZBTB20-CD200R1-20-GORE | 20 (40 μL) | 200 μL |
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| ZBTB20-CD200R1-20-GOOR | 20 (40 μL) | 200 μL |
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| ZBTB20-CD200R1-20-GOGO | 20 (40 μL) | 200 μL |
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| ZBTB20-CD200R1-20-GOGR | 20 (40 μL) | 200 μL |
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| ZBTB20-CD200R1-20-GOAQ | 20 (40 μL) | 200 μL |
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| ZBTB20-CD200R1-20-GRRE | 20 (40 μL) | 200 μL |
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| ZBTB20-CD200R1-20-GROR | 20 (40 μL) | 200 μL |
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| ZBTB20-CD200R1-20-GRGO | 20 (40 μL) | 200 μL |
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| ZBTB20-CD200R1-20-GRGR | 20 (40 μL) | 200 μL |
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| ZBTB20-CD200R1-20-GRAQ | 20 (40 μL) | 200 μL |
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| ZBTB20-CD200R1-20-AQRE | 20 (40 μL) | 200 μL |
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| ZBTB20-CD200R1-20-AQOR | 20 (40 μL) | 200 μL |
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| ZBTB20-CD200R1-20-AQGO | 20 (40 μL) | 200 μL |
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| ZBTB20-CD200R1-20-AQGR | 20 (40 μL) | 200 μL |
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| ZBTB20-CD200R1-20-AQAQ | 20 (40 μL) | 200 μL |
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ZBTB20 Gene Summary
This gene, which was initially designated as dendritic cell-derived BTB/POZ zinc finger (DPZF), belongs to a family of transcription factors with an N-terminal BTB/POZ domain and a C-terminal DNA-bindng zinc finger domain. The BTB/POZ domain is a hydrophobic region of approximately 120 aa which mediates association with other BTB/POZ domain-containing proteins. This gene acts as a transcriptional repressor and plays a role in many processes including neurogenesis, glucose homeostasis, and postnatal growth. Mutations in this gene have been associated with Primrose syndrome as well as the 3q13.31 microdeletion syndrome. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Feb 2017]
Gene Name: Zinc Finger And BTB Domain Containing 20
Chromosome: CHR3: 114056946 -114866127
Locus: 3q13.31
CD200R1 Gene Summary
This gene encodes a receptor for the OX-2 membrane glycoprotein. Both the receptor and substrate are cell surface glycoproteins containing two immunoglobulin-like domains. This receptor is restricted to the surfaces of myeloid lineage cells and the receptor-substrate interaction may function as a myeloid downregulatory signal. Mouse studies of a related gene suggest that this interaction may control myeloid function in a tissue-specific manner. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2008]
Gene Name: CD200 Receptor 1
Chromosome: CHR3: 112641531 -112693937
Locus: 3q13.2
Gene Diseases
The ZBTB20 CD200R1 Fusion has been associated with the following diseases:
| Disease Name |
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| Kidney Renal Clear Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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