ZBTB2-AKAP12 Fusion FISH Probe
The ZBTB2-AKAP12 Fusion FISH Probe is used to confirm a fusion of the ZBTB2 and AKAP12 genes. The fusion of the ZBTB2 and AKAP12 genes has been associated with Stomach Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ZBTB2-AKAP12-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ZBTB2-AKAP12-20-RERE | 20 (40 μL) | 200 μL |
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| ZBTB2-AKAP12-20-REOR | 20 (40 μL) | 200 μL |
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| ZBTB2-AKAP12-20-REGO | 20 (40 μL) | 200 μL |
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| ZBTB2-AKAP12-20-REGR | 20 (40 μL) | 200 μL |
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| ZBTB2-AKAP12-20-REAQ | 20 (40 μL) | 200 μL |
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| ZBTB2-AKAP12-20-ORRE | 20 (40 μL) | 200 μL |
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| ZBTB2-AKAP12-20-OROR | 20 (40 μL) | 200 μL |
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| ZBTB2-AKAP12-20-ORGO | 20 (40 μL) | 200 μL |
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| ZBTB2-AKAP12-20-ORAQ | 20 (40 μL) | 200 μL |
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| ZBTB2-AKAP12-20-GORE | 20 (40 μL) | 200 μL |
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| ZBTB2-AKAP12-20-GOOR | 20 (40 μL) | 200 μL |
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| ZBTB2-AKAP12-20-GOGO | 20 (40 μL) | 200 μL |
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| ZBTB2-AKAP12-20-GOGR | 20 (40 μL) | 200 μL |
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| ZBTB2-AKAP12-20-GOAQ | 20 (40 μL) | 200 μL |
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| ZBTB2-AKAP12-20-GRRE | 20 (40 μL) | 200 μL |
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| ZBTB2-AKAP12-20-GROR | 20 (40 μL) | 200 μL |
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| ZBTB2-AKAP12-20-GRGO | 20 (40 μL) | 200 μL |
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| ZBTB2-AKAP12-20-GRGR | 20 (40 μL) | 200 μL |
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| ZBTB2-AKAP12-20-GRAQ | 20 (40 μL) | 200 μL |
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| ZBTB2-AKAP12-20-AQRE | 20 (40 μL) | 200 μL |
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| ZBTB2-AKAP12-20-AQOR | 20 (40 μL) | 200 μL |
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| ZBTB2-AKAP12-20-AQGO | 20 (40 μL) | 200 μL |
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| ZBTB2-AKAP12-20-AQGR | 20 (40 μL) | 200 μL |
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| ZBTB2-AKAP12-20-AQAQ | 20 (40 μL) | 200 μL |
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AKAP12 Gene Summary
The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is expressed in endothelial cells, cultured fibroblasts, and osteosarcoma cells. It associates with protein kinases A and C and phosphatase, and serves as a scaffold protein in signal transduction. This protein and RII PKA colocalize at the cell periphery. This protein is a cell growth-related protein. Antibodies to this protein can be produced by patients with myasthenia gravis. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Gene Name: A-kinase Anchoring Protein 12
Chromosome: CHR6: 151561133 -151679694
Locus: 6q25.1
ZBTB2 Gene Summary
The Zinc Finger And BTB Domain Containing 2 (ZBTB2) gene is located on chr6 :151685249-151712677 at 6q25.1.
Gene Name: Zinc Finger And BTB Domain Containing 2
Chromosome: CHR6: 151685249 -151712677
Locus: 6q25.1
Gene Diseases
The ZBTB2 AKAP12 Fusion has been associated with the following diseases:
| Disease Name |
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| Stomach Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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