YWHAG-RAB11FIP1 Fusion FISH Probe
The YWHAG-RAB11FIP1 Fusion FISH Probe is used to confirm a fusion of the YWHAG and RAB11FIP1 genes. The fusion of the YWHAG and RAB11FIP1 genes has been associated with Ovarian Serous Cystadenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| YWHAG-RAB11FIP1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| YWHAG-RAB11FIP1-20-RERE | 20 (40 μL) | 200 μL |
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| YWHAG-RAB11FIP1-20-REOR | 20 (40 μL) | 200 μL |
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| YWHAG-RAB11FIP1-20-REGO | 20 (40 μL) | 200 μL |
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| YWHAG-RAB11FIP1-20-REGR | 20 (40 μL) | 200 μL |
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| YWHAG-RAB11FIP1-20-REAQ | 20 (40 μL) | 200 μL |
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| YWHAG-RAB11FIP1-20-ORRE | 20 (40 μL) | 200 μL |
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| YWHAG-RAB11FIP1-20-OROR | 20 (40 μL) | 200 μL |
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| YWHAG-RAB11FIP1-20-ORGO | 20 (40 μL) | 200 μL |
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| YWHAG-RAB11FIP1-20-ORAQ | 20 (40 μL) | 200 μL |
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| YWHAG-RAB11FIP1-20-GORE | 20 (40 μL) | 200 μL |
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| YWHAG-RAB11FIP1-20-GOOR | 20 (40 μL) | 200 μL |
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| YWHAG-RAB11FIP1-20-GOGO | 20 (40 μL) | 200 μL |
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| YWHAG-RAB11FIP1-20-GOGR | 20 (40 μL) | 200 μL |
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| YWHAG-RAB11FIP1-20-GOAQ | 20 (40 μL) | 200 μL |
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| YWHAG-RAB11FIP1-20-GRRE | 20 (40 μL) | 200 μL |
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| YWHAG-RAB11FIP1-20-GROR | 20 (40 μL) | 200 μL |
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| YWHAG-RAB11FIP1-20-GRGO | 20 (40 μL) | 200 μL |
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| YWHAG-RAB11FIP1-20-GRGR | 20 (40 μL) | 200 μL |
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| YWHAG-RAB11FIP1-20-GRAQ | 20 (40 μL) | 200 μL |
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| YWHAG-RAB11FIP1-20-AQRE | 20 (40 μL) | 200 μL |
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| YWHAG-RAB11FIP1-20-AQOR | 20 (40 μL) | 200 μL |
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| YWHAG-RAB11FIP1-20-AQGO | 20 (40 μL) | 200 μL |
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| YWHAG-RAB11FIP1-20-AQGR | 20 (40 μL) | 200 μL |
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| YWHAG-RAB11FIP1-20-AQAQ | 20 (40 μL) | 200 μL |
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YWHAG Gene Summary
This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100% identical to the rat ortholog. It is induced by growth factors in human vascular smooth muscle cells, and is also highly expressed in skeletal and heart muscles, suggesting an important role for this protein in muscle tissue. It has been shown to interact with RAF1 and protein kinase C, proteins involved in various signal transduction pathways. [provided by RefSeq, Jul 2008]
Gene Name: Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase Activation Protein Gamma
Chromosome: CHR7: 75956107 -75988342
Locus: 7q11.23
RAB11FIP1 Gene Summary
This gene encodes one of the Rab11-family interacting proteins (Rab11-FIPs), which play a role in the Rab-11 mediated recycling of vesicles. The encoded protein may be involved in endocytic sorting, trafficking of proteins including integrin subunits and epidermal growth factor receptor (EGFR), and transport between the recycling endosome and the trans-Golgi network. Alternative splicing results in multiple transcript variants. A pseudogene is described on the X chromosome. [provided by RefSeq, Dec 2013]
Gene Name: RAB11 Family Interacting Protein 1
Chromosome: CHR8: 37716464 -37757015
Locus: 8p11.23
Gene Diseases
The YWHAG RAB11FIP1 Fusion has been associated with the following diseases:
| Disease Name |
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| Ovarian Serous Cystadenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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