YWHAB-GLO1 Fusion FISH Probe
The YWHAB-GLO1 Fusion FISH Probe is used to confirm a fusion of the YWHAB and GLO1 genes. The fusion of the YWHAB and GLO1 genes has been associated with Colon Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| YWHAB-GLO1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| YWHAB-GLO1-20-RERE | 20 (40 μL) | 200 μL |
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| YWHAB-GLO1-20-REOR | 20 (40 μL) | 200 μL |
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| YWHAB-GLO1-20-REGO | 20 (40 μL) | 200 μL |
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| YWHAB-GLO1-20-REGR | 20 (40 μL) | 200 μL |
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| YWHAB-GLO1-20-REAQ | 20 (40 μL) | 200 μL |
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| YWHAB-GLO1-20-ORRE | 20 (40 μL) | 200 μL |
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| YWHAB-GLO1-20-OROR | 20 (40 μL) | 200 μL |
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| YWHAB-GLO1-20-ORGO | 20 (40 μL) | 200 μL |
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| YWHAB-GLO1-20-ORAQ | 20 (40 μL) | 200 μL |
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| YWHAB-GLO1-20-GORE | 20 (40 μL) | 200 μL |
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| YWHAB-GLO1-20-GOOR | 20 (40 μL) | 200 μL |
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| YWHAB-GLO1-20-GOGO | 20 (40 μL) | 200 μL |
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| YWHAB-GLO1-20-GOGR | 20 (40 μL) | 200 μL |
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| YWHAB-GLO1-20-GOAQ | 20 (40 μL) | 200 μL |
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| YWHAB-GLO1-20-GRRE | 20 (40 μL) | 200 μL |
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| YWHAB-GLO1-20-GROR | 20 (40 μL) | 200 μL |
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| YWHAB-GLO1-20-GRGO | 20 (40 μL) | 200 μL |
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| YWHAB-GLO1-20-GRGR | 20 (40 μL) | 200 μL |
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| YWHAB-GLO1-20-GRAQ | 20 (40 μL) | 200 μL |
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| YWHAB-GLO1-20-AQRE | 20 (40 μL) | 200 μL |
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| YWHAB-GLO1-20-AQOR | 20 (40 μL) | 200 μL |
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| YWHAB-GLO1-20-AQGO | 20 (40 μL) | 200 μL |
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| YWHAB-GLO1-20-AQGR | 20 (40 μL) | 200 μL |
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| YWHAB-GLO1-20-AQAQ | 20 (40 μL) | 200 μL |
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GLO1 Gene Summary
The enzyme encoded by this gene is responsible for the catalysis and formation of S-lactoyl-glutathione from methylglyoxal condensation and reduced glutatione. Glyoxalase I is linked to HLA and is localized to 6p21.3-p21.1, between HLA and the centromere. [provided by RefSeq, Jul 2008]
Gene Name: Glyoxalase I
Chromosome: CHR6: 38643701 -38670952
Locus: 6p21.2
YWHAB Gene Summary
This gene encodes a protein belonging to the 14-3-3 family of proteins, members of which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals. The encoded protein has been shown to interact with RAF1 and CDC25 phosphatases, suggesting that it may play a role in linking mitogenic signaling and the cell cycle machinery. Two transcript variants, which encode the same protein, have been identified for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase Activation Protein Beta
Chromosome: CHR20: 43514343 -43537161
Locus: 20q13.12
Gene Diseases
The YWHAB GLO1 Fusion has been associated with the following diseases:
| Disease Name |
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| Colon Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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