YEATS4-LYZ Fusion FISH Probe
The YEATS4-LYZ Fusion FISH Probe is used to confirm a fusion of the YEATS4 and LYZ genes. The fusion of the YEATS4 and LYZ genes has been associated with Liver Hepatocellular Carcinoma, Stomach Adenocarcinoma, and Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| YEATS4-LYZ-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| YEATS4-LYZ-20-RERE | 20 (40 μL) | 200 μL |
|
|
| YEATS4-LYZ-20-REOR | 20 (40 μL) | 200 μL |
|
|
| YEATS4-LYZ-20-REGO | 20 (40 μL) | 200 μL |
|
|
| YEATS4-LYZ-20-REGR | 20 (40 μL) | 200 μL |
|
|
| YEATS4-LYZ-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| YEATS4-LYZ-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| YEATS4-LYZ-20-OROR | 20 (40 μL) | 200 μL |
|
|
| YEATS4-LYZ-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| YEATS4-LYZ-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| YEATS4-LYZ-20-GORE | 20 (40 μL) | 200 μL |
|
|
| YEATS4-LYZ-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| YEATS4-LYZ-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| YEATS4-LYZ-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| YEATS4-LYZ-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| YEATS4-LYZ-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| YEATS4-LYZ-20-GROR | 20 (40 μL) | 200 μL |
|
|
| YEATS4-LYZ-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| YEATS4-LYZ-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| YEATS4-LYZ-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| YEATS4-LYZ-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| YEATS4-LYZ-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| YEATS4-LYZ-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| YEATS4-LYZ-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| YEATS4-LYZ-20-AQAQ | 20 (40 μL) | 200 μL |
|
LYZ Gene Summary
This gene encodes human lysozyme, whose natural substrate is the bacterial cell wall peptidoglycan (cleaving the beta[1-4]glycosidic linkages between N-acetylmuramic acid and N-acetylglucosamine). Lysozyme is one of the antimicrobial agents found in human milk, and is also present in spleen, lung, kidney, white blood cells, plasma, saliva, and tears. The protein has antibacterial activity against a number of bacterial species. Missense mutations in this gene have been identified in heritable renal amyloidosis. [provided by RefSeq, Oct 2014]
Gene Name: Lysozyme
Chromosome: CHR12: 69742133 -69748013
Locus: 12q15
YEATS4 Gene Summary
The protein encoded by this gene is found in the nucleoli. It has high sequence homology to human MLLT1, and yeast and human MLLT3 proteins. Both MLLT1 and MLLT3 proteins belong to a class of transcription factors, indicating that the encoded protein might also represent a transcription factor. This protein is thought to be required for RNA transcription. This gene has been shown to be amplified in tumors. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2014]
Gene Name: YEATS Domain Containing 4
Chromosome: CHR12: 69753531 -69784576
Locus: 12q15
Gene Diseases
The YEATS4 LYZ Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Liver Hepatocellular Carcinoma |
| Stomach Adenocarcinoma |
| Bladder Urothelial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|